Literature DB >> 17706677

Neurological course of long-term surviving patients with SCLC and anti-Hu syndrome.

A Poepel1, S Jarius, L C Heukamp, H Urbach, C E Elger, C G Bien, R Voltz.   

Abstract

Patients with small-cell lung cancer (SCLC) have a poor prognosis with a three year survival rate of 4%. Our report concerns three patients with histologically proven SCLC and anti-Hu associated paraneoplastic neurological syndrome who have survived for 11 in two cases and 16 years respectively. The patients showed progressive deterioration which was only partly beneficially modulated by steroid therapy or tumor treatment, even in the cases with complete tumor remission.

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Year:  2007        PMID: 17706677     DOI: 10.1016/j.jns.2007.07.007

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  11 in total

Review 1.  Autoimmune epilepsies.

Authors:  Christian G Bien; Jan Bauer
Journal:  Neurotherapeutics       Date:  2014-04       Impact factor: 7.620

2.  Treatment of paraneoplastic neurologic disorders.

Authors:  John E Greenlee
Journal:  Curr Treat Options Neurol       Date:  2010-05       Impact factor: 3.598

3.  Double trouble: para-neoplastic anti-PCA-2 and CRMP-5-mediated small fibre neuropathy followed by chorea associated with small cell lung cancer and evolving radiological features.

Authors:  Waqar Waheed; James Boyd; Farrah Khan; Sharon L Mount; Neil M Borden; Rup Tandan
Journal:  BMJ Case Rep       Date:  2016-08-29

Review 4.  [Paraneoplastic neurological syndromes].

Authors:  O Stich; S Rauer
Journal:  Nervenarzt       Date:  2013-04       Impact factor: 1.214

5.  [Pathophysiology of antibody-associated diseases of the central nervous system].

Authors:  C G Bien; J Bauer
Journal:  Nervenarzt       Date:  2013-04       Impact factor: 1.214

Review 6.  [Paraneoplastic neurological syndromes and autoimmune encephalitis].

Authors:  O Stich; S Rauer
Journal:  Nervenarzt       Date:  2014-04       Impact factor: 1.214

Review 7.  'Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 2: Anti-PKC-gamma, anti-GluR-delta2, anti-Ca/ARHGAP26 and anti-VGCC.

Authors:  S Jarius; B Wildemann
Journal:  J Neuroinflammation       Date:  2015-09-17       Impact factor: 8.322

8.  Proliferative response of peripheral blood mononuclear cells in anti-Hu antibody-associated patients with paraneoplastic neurological syndrome and their depressant effect on small cell lung cancer cells.

Authors:  Liang Yin; Hongdang Qu; Qiming Chen
Journal:  Mol Med Rep       Date:  2014-11-19       Impact factor: 2.952

9.  Paraneoplastic neurological syndromes: a single institution 10-year case series.

Authors:  Amy M Chan; Joachim M Baehring
Journal:  J Neurooncol       Date:  2019-01-03       Impact factor: 4.130

10.  Small Cell Lung Cancer Accompanied by Tonsillar Metastasis and Anti-Hu Antibody-Associated Paraneoplastic Neuropathy: A Rare Case Report With Long-Term Survival.

Authors:  Jianjiao Ni; Linqian Weng; Mingsheng Liu; Hua Yang; Yingyi Wang
Journal:  Medicine (Baltimore)       Date:  2015-12       Impact factor: 1.817

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