Literature DB >> 17705706

Transfected cell microarrays: an efficient tool for high-throughput functional analysis.

Vytaute Starkuviene1, Rainer Pepperkok, Holger Erfle.   

Abstract

Transfected cell microarrays are considered to be a breakthrough methodology for high-throughput and high-content functional genomics. Here, recent advances in the cell microarray field are reviewed, along with its potential to increase the speed of determining gene function. These advances, combined with an increasing number and diversity of gene perturbing systems, such as RNAi and ectopic gene expression, provide tools for expanding our understanding of biology at the systems level.

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Year:  2007        PMID: 17705706     DOI: 10.1586/14789450.4.4.479

Source DB:  PubMed          Journal:  Expert Rev Proteomics        ISSN: 1478-9450            Impact factor:   3.940


  8 in total

1.  Microengineering methods for cell-based microarrays and high-throughput drug-screening applications.

Authors:  Feng Xu; JinHui Wu; ShuQi Wang; Naside Gozde Durmus; Umut Atakan Gurkan; Utkan Demirci
Journal:  Biofabrication       Date:  2011-07-01       Impact factor: 9.954

Review 2.  Direct assembling methodologies for high-throughput bioscreening.

Authors:  Jorge I Rodríguez-Dévora; Zhi-dong Shi; Tao Xu
Journal:  Biotechnol J       Date:  2011-10-21       Impact factor: 4.677

Review 3.  Manipulating biological agents and cells in micro-scale volumes for applications in medicine.

Authors:  Savas Tasoglu; Umut Atakan Gurkan; Shuqi Wang; Utkan Demirci
Journal:  Chem Soc Rev       Date:  2013-07-07       Impact factor: 54.564

4.  A rapid microwell fluorescence immunoassay for cellular protein detection.

Authors:  Carole Lavigne; de Arméle Guignée; Alain R Thierry
Journal:  Biol Proced Online       Date:  2008-09-22       Impact factor: 3.244

5.  Development of an image-based screening system for inhibitors of the plastidial MEP pathway and of protein geranylgeranylation.

Authors:  Michael Hartmann; Elisabet Gas-Pascual; Andrea Hemmerlin; Michel Rohmer; Thomas J Bach
Journal:  F1000Res       Date:  2015-01-16

Review 6.  Living Cell Microarrays: An Overview of Concepts.

Authors:  Rebecca Jonczyk; Tracy Kurth; Antonina Lavrentieva; Johanna-Gabriela Walter; Thomas Scheper; Frank Stahl
Journal:  Microarrays (Basel)       Date:  2016-05-26

Review 7.  Recent Advances in Multicellular Tumor Spheroid Generation for Drug Screening.

Authors:  Kwang-Ho Lee; Tae-Hyung Kim
Journal:  Biosensors (Basel)       Date:  2021-11-11

8.  Functional studies on transfected cell microarray analysed by linear regression modelling.

Authors:  Christina Saeten Fjeldbo; Kristine Misund; Clara-Cecilie Günther; Mette Langaas; Tonje Strømmen Steigedal; Liv Thommesen; Astrid Laegreid; Torunn Bruland
Journal:  Nucleic Acids Res       Date:  2008-07-15       Impact factor: 16.971

  8 in total

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