Literature DB >> 17705148

Antioxidant and neurosedative properties of polyphenols and iridoids from Lippia alba.

Thierry Hennebelle1, Sevser Sahpaz, Bernard Gressier, Henry Joseph, François Bailleul.   

Abstract

The neurosedative and antioxidative properties of some major compounds isolated from a citral chemotype of Lippia alba were investigated. Binding assays were performed on two CNS inhibitory targets: benzodiazepine and GABA(A) receptors. The most active compound was luteolin-7-diglucuronide, with half maximal inhibitory concentrations (IC(50)) of 101 and 40 microm, respectively. Fifteen compounds isolated from Lippia alba were tested for their radical scavenging capacities against DPPH. Four of the major compounds (verbascoside, calceolarioside E, luteolin-7-diglucuronide and theveside) were also tested for their antioxidant activity against superoxide radical-anion in cell-free (hypoxanthine-xanthine oxidase) and cellular (PMA-stimulated neutrophil granulocytes) systems.

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Year:  2008        PMID： 17705148     DOI： 10.1002/ptr.2266

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  8 in total

1.  Folk medicinal uses of Verbenaceae family plants in Bangladesh.

Authors:  Mohammed Rahmatullah; Rownak Jahan; F M Safiul Azam; S Hossan; M A H Mollik; Taufiq Rahman
Journal:  Afr J Tradit Complement Altern Med       Date:  2011-07-03

2.  Synergistic antibacterial effects of herbal extracts and antibiotics on methicillin-resistant Staphylococcus aureus: A computational and experimental study.

Authors:  Chiu-Fai Kuok; Sai-On Hoi; Chi-Fai Hoi; Chi-Hong Chan; Io-Hong Fong; Cheong-Kei Ngok; Li-Rong Meng; Pedro Fong
Journal:  Exp Biol Med (Maywood)       Date:  2017-01-01

3.  Chemical, microbiological, and sensory parameters during the refrigerated storage of silver catfish (Rhamdia quelen) exposed in vivo to the essential oil of Lippia alba.

Authors:  Ana Paula de Lima Veeck; Ana Paula Daniel; Bruna Klein; Andréia Quatrin; Ana Paula de Souza Rezer; Liana Guidolin Milani; Carla Cristina Zeppenfeld; Mauro Alves da Cunha; Clarissa Giesel Heldwein; Berta Maria Heinzmann; Thaylise Vey Parodi; Bernardo Baldisserotto; Tatiana Emanuelli
Journal:  J Food Sci Technol       Date:  2018-02-03       Impact factor: 2.701

4.  Chemical composition and antigenotoxic properties of Lippia alba essential oils.

Authors:  Molkary Andrea López; Elena E Stashenko; Jorge Luis Fuentes
Journal:  Genet Mol Biol       Date:  2011-07-01       Impact factor: 1.771

Review 5.  Interaction of Plant Extracts with Central Nervous System Receptors.

Authors:  Kenneth Lundstrom; Huyen Thanh Pham; Long Doan Dinh
Journal:  Medicines (Basel)       Date:  2017-02-23

Review 6.  Flavonoids and Phenolic Acids from Oregano: Occurrence, Biological Activity and Health Benefits.

Authors:  Erick P Gutiérrez-Grijalva; Manuel A Picos-Salas; Nayely Leyva-López; Marilyn S Criollo-Mendoza; Gabriela Vazquez-Olivo; J Basilio Heredia
Journal:  Plants (Basel)       Date:  2017-12-26

7.  Cytotoxic Activity of Polyphenol Extracts from Three Oregano Species: Hedeoma patens, Lippia graveolens and Lippia palmeri, and Antiproliferative Potential of Lippia graveolens against Two Types of Breast Cancer Cell Lines (MDA-MB-231 and MCF-7).

Authors:  Marilyn S Criollo-Mendoza; Rosalío Ramos-Payán; Laura A Contreras-Angulo; Erick P Gutiérrez-Grijalva; Josefina León-Félix; Claudia Villicaña; Miguel A Angulo-Escalante; J Basilio Heredia
Journal:  Molecules       Date:  2022-08-17       Impact factor: 4.927

Review 8.  A Review on the Phytochemistry, Pharmacology, Pharmacokinetics and Toxicology of Geniposide, a Natural Product.

Authors:  Mingqiu Shan; Sheng Yu; Hui Yan; Sheng Guo; Wei Xiao; Zhenzhong Wang; Li Zhang; Anwei Ding; Qinan Wu; Sam Fong Yau Li
Journal:  Molecules       Date:  2017-10-10       Impact factor: 4.411
  8 in total

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