Literature DB >> 17704328

Reconstruction of doses from ionizing radiation using fluorescence in situ hybridization techniques.

A A Edwards1, M Szluinska, D C Lloyd.   

Abstract

This paper reviews cytogenetic methods of biological dosimetry. The most reliable indicator of exposure to ionizing radiation is the observation of dicentrics in human peripheral lymphocytes. The major disadvantage is that dicentrics cannot be used for exposures that occur many years prior to blood sampling. In such cases, translocations are the aberrations of choice, and recent developments in their measurement using fluorescence in situ hybridization techniques are highlighted.

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Mesh：

Year:  2007        PMID： 17704328     DOI： 10.1259/bjr/24766640

Source DB:  PubMed          Journal:  Br J Radiol        ISSN： 0007-1285            Impact factor:   3.039


  8 in total

Review 1.  Quantitative modeling of chronic myeloid leukemia: insights from radiobiology.

Authors:  Tomas Radivoyevitch; Lynn Hlatky; Julian Landaw; Rainer K Sachs
Journal:  Blood       Date:  2012-02-21       Impact factor: 22.113

2.  Verification by the FISH translocation assay of historic doses to Mayak workers from external gamma radiation.

Authors:  Natalia V Sotnik; Tamara V Azizova; Firouz Darroudi; Elizabeth A Ainsbury; Jayne E Moquet; Janna Fomina; David C Lloyd; Pat A Hone; Alan A Edwards
Journal:  Radiat Environ Biophys       Date:  2015-08-30       Impact factor: 1.925

3.  Seventeen-year follow-up study on chromosomal aberrations in five victims accidentally exposed to several Gy of 60Co gamma-rays.

Authors:  Ying Chen; Cui-Zhen Jin; Xue-Qing Zhang; Shi-Li Ge; Ze-Yun Zhang; Hui Xu; Xiu-Lin Liu; De-Chang Wu; Ping-Kun Zhou
Journal:  Radiat Environ Biophys       Date:  2008-11-13       Impact factor: 1.925

4.  Chromosome aberrations in workers with exposure to α-particle radiation from internal deposits of plutonium: expectations from in vitro studies and comparisons with workers with predominantly external γ-radiation exposure.

Authors:  Gillian B Curwen; Natalia V Sotnik; Kevin K Cadwell; Tamara V Azizova; Mark A Hill; E Janet Tawn
Journal:  Radiat Environ Biophys       Date:  2015-02-04       Impact factor: 1.925

5.  Dicentric Dose Estimates for Patients Undergoing Radiotherapy in the RTGene Study to Assess Blood Dosimetric Models and the New Bayesian Method for Gradient Exposure.

Authors:  Jayne Moquet; Manuel Higueras; Ellen Donovan; Sue Boyle; Stephen Barnard; Clare Bricknell; Mingzhu Sun; Lone Gothard; Grainne O'Brien; Lourdes Cruz-Garcia; Christophe Badie; Elizabeth Ainsbury; Navita Somaiah
Journal:  Radiat Res       Date:  2018-09-20       Impact factor: 2.841

6.  mFISH analysis of chromosome aberrations in workers occupationally exposed to mixed radiation.

Authors:  Natalia V Sotnik; Sergey V Osovets; Harry Scherthan; Tamara V Azizova
Journal:  Radiat Environ Biophys       Date:  2014-04-09       Impact factor: 1.925

7.  Chromosome Aberrations in a Group of People Exposed to Radioactive Releases from the Three Mile Island Nuclear Accident and Inferences for Radiation Effects.

Authors:  Mark P Little; Richard Wakeford; Maureen Hatch; Elizabeth A Ainsbury; E Janet Tawn
Journal:  Radiat Res       Date:  2021-06-01       Impact factor: 3.372

8.  Chromosome aberrations determined by sFISH and G-banding in lymphocytes from workers with internal deposits of plutonium.

Authors:  E Janet Tawn; Gillian B Curwen; Patricia Jonas; Anthony E Riddell; Leanne Hodgson
Journal:  Int J Radiat Biol       Date:  2016-04-04       Impact factor: 2.694
  8 in total

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