Literature DB >> 17702738

Use of antimicrobial catheter lock solutions to prevent catheter-related bacteremia.

Anthony J Bleyer1.   

Abstract

Catheter-related bacteremia is an important source of morbidity and mortality in hemodialysis patients. A number of well-designed, controlled, prospective trials using antimicrobial catheter lock solutions to prevent catheter-related bacteremia have shown a dramatic, statistically significant decrease in not only infection but also mortality related to catheter-related bacteremia. Despite evidence of significant benefit, these locks are not routinely used in the United States. This review describes the epidemic problem of catheter-related bacteremia, reviews recent clinical trials with antimicrobial catheter lock solutions, and discusses current options and potential indications for catheter lock solutions in the hemodialysis population.

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Year:  2007        PMID： 17702738     DOI： 10.2215/CJN.00290107

Source DB:  PubMed          Journal:  Clin J Am Soc Nephrol        ISSN： 1555-9041            Impact factor:   8.237


  12 in total

1.  Stability of trisodium citrate and gentamicin solution for catheter locks after storage in plastic syringes at room temperature.

Authors:  Dennis Cote; Charmaine E Lok; Marisa Battistella; Lavern Vercaigne
Journal:  Can J Hosp Pharm       Date:  2010-07

2.  Dialysis: Are prophylactic gentamicin catheter locks safe?

Authors:  Michael Allon
Journal:  Nat Rev Nephrol       Date:  2010-11-09       Impact factor: 28.314

3.  Quasi-experimental study of sodium citrate locks and the risk of acute hemodialysis catheter infection among critically ill patients.

Authors:  Jean-Jacques Parienti; Stéphanie Deryckère; Bruno Mégarbane; Xavier Valette; Amélie Seguin; Bertrand Sauneuf; Jean-Paul Mira; Bertrand Souweine; Vincent Cattoir; Cédric Daubin; Damien du Cheyron
Journal:  Antimicrob Agents Chemother       Date:  2014-06-30       Impact factor: 5.191

4.  In Vitro Approach for Identification of the Most Effective Agents for Antimicrobial Lock Therapy in the Treatment of Intravascular Catheter-Related Infections Caused by Staphylococcus aureus.

Authors:  S Hogan; M Zapotoczna; N T Stevens; H Humphreys; J P O'Gara; E O'Neill
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

5.  Daptomycin antibiotic lock therapy in a rat model of staphylococcal central venous catheter biofilm infections.

Authors:  Andrew D G Van Praagh; Tongchuan Li; Shuxin Zhang; Anu Arya; Liping Chen; Xi-Xian Zhang; Shellie Bertolami; Lawrence I Mortin
Journal:  Antimicrob Agents Chemother       Date:  2011-06-27       Impact factor: 5.191

6.  Efficacy of ethanol against Candida albicans and Staphylococcus aureus polymicrobial biofilms.

Authors:  Brian M Peters; Raven M Ward; Hallie S Rane; Samuel A Lee; Mairi C Noverr
Journal:  Antimicrob Agents Chemother       Date:  2012-10-15       Impact factor: 5.191

7.  Prevention of catheter-related bacteremia in children on hemodialysis: time for action.

Authors:  Constantinos J Stefanidis
Journal:  Pediatr Nephrol       Date:  2009-07-23       Impact factor: 3.714

8.  Successful prevention of tunneled central catheter infection by antibiotic lock therapy using cefazolin and gentamicin.

Authors:  T N V Silva; M L Mendes; J M G Abrão; J T Caramori; D Ponce
Journal:  Int Urol Nephrol       Date:  2012-12-27       Impact factor: 2.370

Review 9.  Hemodialysis vascular access options in pediatrics: considerations for patients and practitioners.

Authors:  Deepa H Chand; Rudolph P Valentini; Elaine S Kamil
Journal:  Pediatr Nephrol       Date:  2008-04-08       Impact factor: 3.714

10.  Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens).

Authors:  Janusz Steczko; Stephen R Ash; David E Nivens; Lloyd Brewer; Roland K Winger
Journal:  Nephrol Dial Transplant       Date:  2009-01-30       Impact factor: 5.992
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