Literature DB >> 17702552

Semi-supervised learning of the hidden vector state model for extracting protein-protein interactions.

Deyu Zhou1, Yulan He, Chee Keong Kwoh.   

Abstract

OBJECTIVE: The hidden vector state (HVS) model is an extension of the basic discrete Markov model in which context is encoded as a stack-oriented state vector. It has been applied successfully for protein-protein interactions extraction. However, the HVS model, being a statistically based approach, requires large-scale annotated corpora in order to reliably estimate model parameters. This is normally difficult to obtain in practical applications. METHODS AND MATERIALS: In this paper, we present two novel semi-supervised learning approaches, one based on classification and the other based on expectation-maximization, to train the HVS model from both annotated and un-annotated corpora. RESULTS AND
CONCLUSION: Experimental results show the improved performance over the baseline system using the HVS model trained solely from the annotated corpus, which gives the support to the feasibility and efficiency of our approaches.

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Year:  2007        PMID: 17702552     DOI: 10.1016/j.artmed.2007.07.004

Source DB:  PubMed          Journal:  Artif Intell Med        ISSN: 0933-3657            Impact factor:   5.326


  1 in total

1.  Combining active learning and semi-supervised learning techniques to extract protein interaction sentences.

Authors:  Min Song; Hwanjo Yu; Wook-Shin Han
Journal:  BMC Bioinformatics       Date:  2011-11-24       Impact factor: 3.169

  1 in total

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