OBJECTIVES: While depression and apathy are common after stroke, past studies have done little to examine the influence of these two symptoms on functional outcome respectively. This study was designed to examine the effect of depression or apathy on functional recovery after stroke in 237 Japanese stroke patients. METHODS: We assessed the psychological status using self-rating scales [the Zung Self-Rating Depression Scale (SDS) for depression and the Apathy Scale (AS) for apathy] and an observer-rating scale [the Neuropsychiatric Inventory (NPI)]. We assessed physical disability using the Functional Independence Measurement (FIM). Post-hoc test and multiple regression analysis were used to determine the independent effects of post-stroke depression and apathy on functional outcome. RESULTS: Depression was observed in 75 (31.6%) using SDS and 88 (40.2%) using NPI, and apathy in 95 (40.1%) using AS and 42 (19.2%) using NPI, respectively. Post-hoc test and multiple regression analysis indicated that the cognitive variable (Mini-Mental State Examination: MMSE score) and AS score, but not SDS score, correlated negatively with improvement in FIM. CONCLUSIONS: Apathy might be more frequently associated with functional abilities and likely interact with the recovery process as compared with depression after stroke. Copyright (c) 2007 John Wiley & Sons, Ltd.
OBJECTIVES: While depression and apathy are common after stroke, past studies have done little to examine the influence of these two symptoms on functional outcome respectively. This study was designed to examine the effect of depression or apathy on functional recovery after stroke in 237 Japanese strokepatients. METHODS: We assessed the psychological status using self-rating scales [the Zung Self-Rating Depression Scale (SDS) for depression and the Apathy Scale (AS) for apathy] and an observer-rating scale [the Neuropsychiatric Inventory (NPI)]. We assessed physical disability using the Functional Independence Measurement (FIM). Post-hoc test and multiple regression analysis were used to determine the independent effects of post-stroke depression and apathy on functional outcome. RESULTS:Depression was observed in 75 (31.6%) using SDS and 88 (40.2%) using NPI, and apathy in 95 (40.1%) using AS and 42 (19.2%) using NPI, respectively. Post-hoc test and multiple regression analysis indicated that the cognitive variable (Mini-Mental State Examination: MMSE score) and AS score, but not SDS score, correlated negatively with improvement in FIM. CONCLUSIONS: Apathy might be more frequently associated with functional abilities and likely interact with the recovery process as compared with depression after stroke. Copyright (c) 2007 John Wiley & Sons, Ltd.
Authors: Diana E Clarke; Jean Y Ko; Emily A Kuhl; Robert van Reekum; Rocio Salvador; Robert S Marin Journal: J Psychosom Res Date: 2010-03-31 Impact factor: 3.006
Authors: Genevieve S Yuen; Saumya Bhutani; Bryony J Lucas; Faith M Gunning; Bassem AbdelMalak; Joanna K Seirup; Sibel A Klimstra; George S Alexopoulos Journal: Am J Geriatr Psychiatry Date: 2014-06-26 Impact factor: 4.105
Authors: Ari L Harris; Jessica Elder; Nicholas D Schiff; Jonathan D Victor; Andrew M Goldfine Journal: Transl Stroke Res Date: 2013-10-19 Impact factor: 6.829
Authors: Monica Spruit-van Eijk; Bianca I Buijck; Sytse U Zuidema; Frans L M Voncken; Alexander C H Geurts; Raymond T C M Koopmans Journal: BMC Geriatr Date: 2010-03-27 Impact factor: 3.921