Literature DB >> 17700588

"Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs).

D J Prockop1.   

Abstract

There has recently been an explosion of interest in adult stem/progenitor cells that have the potential to repair tissues, with over 3,000 citations to publications (PubMed) and numerous announcements of clinical trials in which the cells are used to treat individuals with a broad range of diseases. At the same time, the data present a paradox-the cells originally attracted attention because of their stem-cell-like properties, but the cells frequently repair injured tissues without much evidence of either engraftment or differentiation.

Mesh：

Year:  2007        PMID： 17700588     DOI： 10.1038/sj.clpt.6100313

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  108 in total

Review 1.  Multipotent mesenchymal stromal cells and the innate immune system.

Authors:  Katarina Le Blanc; Dimitrios Mougiakakos
Journal:  Nat Rev Immunol       Date:  2012-04-25       Impact factor: 53.106

Review 2.  Cardiac cell therapy: boosting mesenchymal stem cells effects.

Authors:  E Samper; A Diez-Juan; J A Montero; P Sepúlveda
Journal:  Stem Cell Rev Rep       Date:  2013-06       Impact factor: 5.739

3.  Intramuscular VEGF activates an SDF1-dependent progenitor cell cascade and an SDF1-independent muscle paracrine cascade for cardiac repair.

Authors:  David Zisa; Arsalan Shabbir; Michalis Mastri; Tyler Taylor; Ilija Aleksic; Mary McDaniel; Gen Suzuki; Techung Lee
Journal:  Am J Physiol Heart Circ Physiol       Date:  2011-09-30       Impact factor: 4.733

4.  Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair.

Authors:  Arsalan Shabbir; David Zisa; Huey Lin; Michalis Mastri; Gregory Roloff; Gen Suzuki; Techung Lee
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-09-17       Impact factor: 4.733

5.  "Mesenchymal" stem cells in human bone marrow (skeletal stem cells): a critical discussion of their nature, identity, and significance in incurable skeletal disease.

Authors:  Paolo Bianco; Pamela Gehron Robey; Isabella Saggio; Mara Riminucci
Journal:  Hum Gene Ther       Date:  2010-09       Impact factor: 5.695

6.  Mesenchymal stem cells: engineering regeneration.

Authors:  Atta Behfar; Andre Terzic
Journal:  Clin Transl Sci       Date:  2008-05       Impact factor: 4.689

7.  Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cells.

Authors:  Benjamin L Larson; Joni Ylostalo; Ryang H Lee; Carl Gregory; Darwin J Prockop
Journal:  Tissue Eng Part A       Date:  2010-07-13       Impact factor: 3.845

8.  Boot camp for mesenchymal stem cells.

Authors:  Eduardo Marbán; Konstantinos Malliaras
Journal:  J Am Coll Cardiol       Date:  2010-08-24       Impact factor: 24.094

9.  Bone transplantation and tissue engineering, part IV. Mesenchymal stem cells: history in orthopedic surgery from Cohnheim and Goujon to the Nobel Prize of Yamanaka.

Authors:  Philippe Hernigou
Journal:  Int Orthop       Date:  2015-03-07       Impact factor: 3.075

10.  Adipose stem cells used to reconstruct 13 cases with cranio-maxillofacial hard-tissue defects.

Authors:  George K Sándor; Jura Numminen; Jan Wolff; Tuomo Thesleff; Aimo Miettinen; Veikko J Tuovinen; Bettina Mannerström; Mimmi Patrikoski; Riitta Seppänen; Susanna Miettinen; Markus Rautiainen; Juha Öhman
Journal:  Stem Cells Transl Med       Date:  2014-02-20       Impact factor: 6.940
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.