Literature DB >> 17699932

Correlation between serum vitamin D (25(OH)D) concentration and quadriceps femoris muscle strength in Indonesian elderly women living in three nursing homes.

Ikhwan Rinaldi1, Siti Setiati, Maryantoro Oemardi, Wanarani Aries, T Z Tamin.   

Abstract

AIM: to investigate the correlation between serum vitamin D (25(OH)D) concentration and quadriceps femoris muscle strength.
METHODS: this was a cross-sectional correlative study, conducted at three nursing homes in Jakarta and one nursing home in Bekasi in January 2005. The subjects were women aged 60 years or above. Those selected study subjects underwent quadriceps femoris muscle strength examination with Cybex dynamometer with 150 degrees/second speed, twice (three repetitions with 30 second rest time). The 25 (OH)D concentration was measured by ELISA.
RESULTS: out of 67 subjects who met the required criteria for this study, five subjects withdrew from the study during muscle strength examination. The mean age was 71.1 (SD 7.2) years old while the mean serum vitamin D concentration was 68.2 (SD 21.6) nmol/l. Vitamin D deficiency (<or= 50 nmol/l) was found in 22.6% of subjects. It was also found that the median (minimum-maximum) quadriceps femoris muscle strength was 40.00 (11-116) N.m. Approximately 82.3% of the subjects were of generalized muscle weakness. Correlation was found between serum 25 (OH)D concentration and quadriceps femoris muscle strength (r = 0.327; P = 0.009).
CONCLUSION: this study reveals that serum 25 (OH) D concentrations in Indonesian elderly women is correlated with quadriceps femoris muscle strength. The proportion of elderly women with muscle weakness is higher than the normal ones. The group with older age shows higher proportion of muscle weakness. Most subjects have normal serum vitamin D concentration.

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Year:  2007        PMID: 17699932

Source DB:  PubMed          Journal:  Acta Med Indones        ISSN: 0125-9326


  7 in total

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  7 in total

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