Literature DB >> 17699527

Genetic and molecular epidemiology.

John P A Ioannidis1.   

Abstract

Genetic and molecular epidemiology covers a vast area of research. Given the rapid changes in this field, discussing a research agenda is a precarious and ambitious task. A representative set of high-priority concepts will be presented here, each of which alone could be the topic of a long series of essays. The wish list includes issues of full transparency and integration of information, dealing efficiently with complex multidimensional biology, juxtaposing the genome and environmental exposures, and using robust randomised trials to advance our knowledge and its application in this field.

Mesh：

Year:  2007        PMID： 17699527      PMCID： PMC2659995          DOI： 10.1136/jech.2006.059055

Source DB:  PubMed          Journal:  J Epidemiol Community Health        ISSN： 0143-005X            Impact factor:   3.710


  22 in total

1.  Gene Expression Omnibus: NCBI gene expression and hybridization array data repository.

Authors:  Ron Edgar; Michael Domrachev; Alex E Lash
Journal:  Nucleic Acids Res       Date:  2002-01-01       Impact factor: 16.971

2.  Testing drug response in the presence of genetic information: sampling issues for clinical trials.

Authors:  L R Cardon; R M Idury; T J Harris; J S Witte; R C Elston
Journal:  Pharmacogenetics       Date:  2000-08

3.  'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?

Authors:  George Davey Smith; Shah Ebrahim
Journal:  Int J Epidemiol       Date:  2003-02       Impact factor: 7.196

Review 4.  Pitfalls in the use of DNA microarray data for diagnostic and prognostic classification.

Authors:  Richard Simon; Michael D Radmacher; Kevin Dobbin; Lisa M McShane
Journal:  J Natl Cancer Inst       Date:  2003-01-01       Impact factor: 13.506

5.  Systems biology and new technologies enable predictive and preventative medicine.

Authors:  Leroy Hood; James R Heath; Michael E Phelps; Biaoyang Lin
Journal:  Science       Date:  2004-10-22       Impact factor: 47.728

6.  Microarrays and molecular research: noise discovery?

Authors:  John P A Ioannidis
Journal:  Lancet       Date:  2005 Feb 5-11       Impact factor: 79.321

Review 7.  Bias as a threat to the validity of cancer molecular-marker research.

Authors:  David F Ransohoff
Journal:  Nat Rev Cancer       Date:  2005-02       Impact factor: 60.716

8.  Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.

Authors:  Lars Bertram; Matthew B McQueen; Kristina Mullin; Deborah Blacker; Rudolph E Tanzi
Journal:  Nat Genet       Date:  2007-01       Impact factor: 38.330

9.  ArrayExpress--a public repository for microarray gene expression data at the EBI.

Authors:  Alvis Brazma; Helen Parkinson; Ugis Sarkans; Mohammadreza Shojatalab; Jaak Vilo; Niran Abeygunawardena; Ele Holloway; Misha Kapushesky; Patrick Kemmeren; Gonzalo Garcia Lara; Ahmet Oezcimen; Philippe Rocca-Serra; Susanna-Assunta Sansone
Journal:  Nucleic Acids Res       Date:  2003-01-01       Impact factor: 16.971

10.  Submission of microarray data to public repositories.

Authors:  Catherine A Ball; Alvis Brazma; Helen Causton; Steve Chervitz; Ron Edgar; Pascal Hingamp; John C Matese; Helen Parkinson; John Quackenbush; Martin Ringwald; Susanna-Assunta Sansone; Gavin Sherlock; Paul Spellman; Chris Stoeckert; Yoshio Tateno; Ronald Taylor; Joseph White; Neil Winegarden
Journal:  PLoS Biol       Date:  2004-08-31       Impact factor: 8.029
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  6 in total

1.  STrengthening the reporting of OBservational studies in Epidemiology-Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement.

Authors:  Valentina Gallo; Matthias Egger; Valerie McCormack; Peter B Farmer; John P A Ioannidis; Micheline Kirsch-Volders; Giuseppe Matullo; David H Phillips; Bernadette Schoket; Ulf Stromberg; Roel Vermeulen; Christopher Wild; Miquel Porta; Paolo Vineis
Journal:  Eur J Epidemiol       Date:  2011-10-29       Impact factor: 8.082

2.  Assessing the social meaning, value and implications of research in genomics.

Authors:  Blanca Lumbreras; Miquel Porta; Ildefonso Hernández-Aguado
Journal:  J Epidemiol Community Health       Date:  2007-09       Impact factor: 3.710

3.  Required sample size and nonreplicability thresholds for heterogeneous genetic associations.

Authors:  Ramal Moonesinghe; Muin J Khoury; Tiebin Liu; John P A Ioannidis
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-03       Impact factor: 11.205

4.  STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology (STROBE-ME): an extension of the STROBE Statement.

Authors:  Valentina Gallo; Matthias Egger; Valerie McCormack; Peter B Farmer; John P A Ioannidis; Micheline Kirsch-Volders; Giuseppe Matullo; David H Phillips; Bernadette Schoket; Ulf Stromberg; Roel Vermeulen; Christopher Wild; Miquel Porta; Paolo Vineis
Journal:  PLoS Med       Date:  2011-10-25       Impact factor: 11.069

5.  Did the reporting of prognostic studies of tumour markers improve since the introduction of REMARK guideline? A comparison of reporting in published articles.

Authors:  Peggy Sekula; Susan Mallett; Douglas G Altman; Willi Sauerbrei
Journal:  PLoS One       Date:  2017-06-14       Impact factor: 3.240

Review 6.  What is epidemiology? Changing definitions of epidemiology 1978-2017.

Authors:  Mathilde Frérot; Annick Lefebvre; Simon Aho; Patrick Callier; Karine Astruc; Ludwig Serge Aho Glélé
Journal:  PLoS One       Date:  2018-12-10       Impact factor: 3.240
  6 in total

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