Literature DB >> 17698930

Evaluation of change in CD4+ cell counts in AIDS clinical trials.

H Liang1.   

Abstract

To evaluate the antiretroviral activity of antiretroviral agents and to compare the effects of two different antiretroviral agents, we propose a non-parametric mixed-effects model to investigate change of CD4+ counts. The proposed model and methods are applied to analyse the data from PACTG345 study. Population and individual patterns of change of CD4+ counts and a reference band are obtained. Our results indicate that treatment with high-dose ritonavir is significantly superior compared with low-dose ritonavir.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17698930      PMCID： PMC2832484          DOI： 10.1177/0962280206075524

Source DB:  PubMed          Journal:  Stat Methods Med Res        ISSN： 0962-2802            Impact factor:   3.021


  12 in total

1.  Nonparametric mixed effects models for unequally sampled noisy curves.

Authors:  J A Rice; C O Wu
Journal:  Biometrics       Date:  2001-03       Impact factor: 2.571

2.  Joint modelling of longitudinal measurements and event time data.

Authors:  R Henderson; P Diggle; A Dobson
Journal:  Biostatistics       Date:  2000-12       Impact factor: 5.899

3.  Natural immunity and HIV disease progression.

Authors:  H Ullum; A Cozzi Lepri; H Aladdin; T Katzenstein; J Victor; A N Phillips; J Gerstoft; P Skinhøj; B Klarlund Pedersen
Journal:  AIDS       Date:  1999-04-01       Impact factor: 4.177

4.  Marker values at the time of an AIDS diagnosis.

Authors:  J M Taylor; D K Kim
Journal:  Stat Med       Date:  1994 Oct 15-30       Impact factor: 2.373

5.  Infrequent detection of HIV-1-specific, but not cytomegalovirus-specific, CD8(+) T cell responses in young HIV-1-infected infants.

Authors:  Z A Scott; E G Chadwick; L L Gibson; M D Catalina; M M McManus; R Yogev; P Palumbo; J L Sullivan; P Britto; H Gay; K Luzuriaga
Journal:  J Immunol       Date:  2001-12-15       Impact factor: 5.422

Review 6.  Inflammatory reactions in HIV-1-infected persons after initiation of highly active antiretroviral therapy.

Authors:  J A DeSimone; R J Pomerantz; T J Babinchak
Journal:  Ann Intern Med       Date:  2000-09-19       Impact factor: 25.391

7.  Direct comparison of time to AIDS and infectious disease death between HIV seroconverter injection drug users in Italy and the United States: results from the ALIVE and ISS studies. AIDS Link to Intravenous Experiences. Italian Seroconversion Study.

Authors:  P Pezzotti; N Galai; D Vlahov; G Rezza; C M Lyles; J Astemborski
Journal:  J Acquir Immune Defic Syndr Hum Retrovirol       Date:  1999-03-01

8.  A randomized study of emtricitabine and lamivudine in stably suppressed patients with HIV.

Authors:  Constance A Benson; Charles van der Horst; Anthony Lamarca; David W Haas; Cheryl K McDonald; Corklin R Steinhart; John Rublein; Joseph B Quinn; Elsa Mondou; Franck Rousseau
Journal:  AIDS       Date:  2004-11-19       Impact factor: 4.177

9.  Dual HIV-1 infection associated with rapid disease progression.

Authors:  Geoffrey S Gottlieb; David C Nickle; Mark A Jensen; Kim G Wong; Jandre Grobler; Fusheng Li; Shan-Lu Liu; Cecilia Rademeyer; Gerald H Learn; Salim S Abdool Karim; Carolyn Williamson; Lawrence Corey; Joseph B Margolick; James I Mullins
Journal:  Lancet       Date:  2004-02-21       Impact factor: 79.321

10.  Joint modelling of bivariate longitudinal data with informative dropout and left-censoring, with application to the evolution of CD4+ cell count and HIV RNA viral load in response to treatment of HIV infection.

Authors:  Rodolphe Thiébaut; Hélène Jacqmin-Gadda; Abdel Babiker; Daniel Commenges
Journal:  Stat Med       Date:  2005-01-15       Impact factor: 2.373
View more
  1 in total

1.  Long-term CD4+ T-cell count evolution after switching from regimens including HIV nucleoside reverse transcriptase inhibitors (NRTI) plus protease inhibitors to regimens containing NRTI plus non-NRTI or only NRTI.

Authors:  Carlo Torti; Antonella d'Arminio-Monforte; Anton L Pozniak; Giuseppe Lapadula; Giuliana Cologni; Andrea Antinori; Andrea De Luca; Cristina Mussini; Antonella Castagna; Paola Cicconi; Lorenzo Minoli; Andrea Costantini; Giampiero Carosi; Hua Liang; Bruno M Cesana
Journal:  BMC Infect Dis       Date:  2011-01-25       Impact factor: 3.090
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.