| Literature DB >> 17698321 |
Josephine M Johns1, Matthew S McMurray, Vivian E Hofler, Thomas M Jarrett, Christopher L Middleton, Deborah L Elliott, Raessa Mirza, Amber Haslup, Jay C Elliott, Cheryl H Walker.
Abstract
Impaired onset of maternal behavior in first generation rat dams was previously correlated with rearing by cocaine-treated dams and prenatal cocaine exposure. Pup-induced maternal behavior in non-lactating rats has not been examined with regard to cocaine exposure and rearing conditions. First generation male and female juveniles and young adult males reared by cocaine-treated or control dams and prenatally exposed to either cocaine or control conditions were tested for pup-induced maternal behavior at postnatal days 28 and 60. We now report disruptions in pup-induced maternal behavior in both 28 and 60 day old first generation offspring attributable to rearing condition and prenatal cocaine exposure.Entities:
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Year: 2007 PMID: 17698321 PMCID: PMC2147063 DOI: 10.1016/j.ntt.2007.07.003
Source DB: PubMed Journal: Neurotoxicol Teratol ISSN: 0892-0362 Impact factor: 3.763