Literature DB >> 17697882

Platelet integrin adhesive functions and signaling.

Nicolas Prévost1, Hisashi Kato, Laurent Bodin, Sanford J Shattil.   

Abstract

Integrin-mediated cellular events affect all cell types and functions, in physiological as well as pathological settings. Blood platelets, because of their unique nature, have proven to be a powerful cell model with which to study the adhesive and signaling properties of integrins. The characterization of the structural and molecular mechanisms regulating the main platelet integrin, alphaIIbbeta3, has provided some essential clues as to how integrins are regulated in general. The present chapter details the various protocols and reagents currently in use in our laboratory to study alphaIIbbeta3 adhesive responses and signaling in both human and murine cell models.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17697882     DOI： 10.1016/S0076-6879(07)26006-9

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  13 in total

1.  What is vinculin needed for in platelets?

Authors:  J V Mitsios; N Prevost; A Kasirer-Friede; E Gutierrez; A Groisman; C S Abrams; Y Wang; R I Litvinov; A Zemljic-Harpf; R S Ross; S J Shattil
Journal:  J Thromb Haemost       Date:  2010-10       Impact factor: 5.824

2.  Dissecting pathways to thrombocytopenia in a mouse model of visceral leishmaniasis.

Authors:  Gulab Fatima Rani; Olivier Preham; Helen Ashwin; Najmeeyah Brown; Ian S Hitchcock; Paul M Kaye
Journal:  Blood Adv       Date:  2021-03-23

3.  Talin and signaling through integrins.

Authors:  Mohamed Bouaouina; David S Harburger; David A Calderwood
Journal:  Methods Mol Biol       Date:  2012

Review 4.  Regulating thrombus growth and stability to achieve an optimal response to injury.

Authors:  L F Brass; K M Wannemacher; P Ma; T J Stalker
Journal:  J Thromb Haemost       Date:  2011-07       Impact factor: 5.824

Review 5.  Harnessing the platelet signaling network to produce an optimal hemostatic response.

Authors:  Lawrence F Brass; Maurizio Tomaiuolo; Timothy J Stalker
Journal:  Hematol Oncol Clin North Am       Date:  2013-04-11       Impact factor: 3.722

Review 6.  Platelet signaling.

Authors:  Timothy J Stalker; Debra K Newman; Peisong Ma; Kenneth M Wannemacher; Lawrence F Brass
Journal:  Handb Exp Pharmacol       Date:  2012

7.  Group IVA cytosolic phospholipase A2 (cPLA2alpha) and integrin alphaIIbbeta3 reinforce each other's functions during alphaIIbbeta3 signaling in platelets.

Authors:  Nicolas Prévost; John V Mitsios; Hisashi Kato; John E Burke; Edward A Dennis; Takao Shimizu; Sanford J Shattil
Journal:  Blood       Date:  2008-10-07       Impact factor: 22.113

8.  Antithrombotic effects of targeting alphaIIbbeta3 signaling in platelets.

Authors:  Ararat J Ablooglu; Jian Kang; Brian G Petrich; Mark H Ginsberg; Sanford J Shattil
Journal:  Blood       Date:  2008-11-12       Impact factor: 22.113

9.  Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo.

Authors:  Hitoshi Takizawa; Satoshi Nishimura; Naoya Takayama; Atsushi Oda; Hidekazu Nishikii; Yohei Morita; Sei Kakinuma; Satoshi Yamazaki; Satoshi Okamura; Noriko Tamura; Shinya Goto; Akira Sawaguchi; Ichiro Manabe; Kiyoshi Takatsu; Hiromitsu Nakauchi; Satoshi Takaki; Koji Eto
Journal:  J Clin Invest       Date:  2009-12-21       Impact factor: 14.808

10.  Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets.

Authors:  Begoña Hurtado; Marianna Trakala; Pilar Ximénez-Embún; Aicha El Bakkali; David Partida; Belén Sanz-Castillo; Mónica Álvarez-Fernández; María Maroto; Ruth Sánchez-Martínez; Lola Martínez; Javier Muñoz; Pablo García de Frutos; Marcos Malumbres
Journal:  J Clin Invest       Date:  2018-10-29       Impact factor: 14.808
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.