Literature DB >> 17697647

Early exposure to pets: good or bad?

Jeremy D Bufford1, James E Gern.   

Abstract

Although pet exposure is known to trigger or worsen allergy symptoms and asthma in patients sensitized to pets, data from recent years has shown that pet exposure in early childhood may actually prevent the development of allergic sensitization and allergic diseases including allergic rhinitis, asthma, and atopic dermatitis. The concept of a protective pet effect remains controversial because these findings have not been duplicated in all studies. Moreover, some studies suggest that pet exposure promotes allergic disease. The protective pet effect may be influenced by multiple factors including type of pet; timing, duration, and intensity of exposure; and genetic factors. The mechanisms behind the protective pet effect remain under investigation but may include alterations in immune development, pet-specific tolerance, and exposure to innate immune stimuli.

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Year:  2007        PMID: 17697647     DOI: 10.1007/s11882-007-0057-4

Source DB:  PubMed          Journal:  Curr Allergy Asthma Rep        ISSN: 1529-7322            Impact factor:   4.806


  55 in total

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Authors:  Ulrike Gehring; Wolfgang Bischof; Bärbel Fahlbusch; Heinz-Erich Wichmann; Joachim Heinrich
Journal:  Am J Respir Crit Care Med       Date:  2002-10-01       Impact factor: 21.405

2.  Indoor allergens, asthma, and asthma-related symptoms among adolescents in Wuhan, China.

Authors:  Päivi M Salo; Jiang Xia; C Anderson Johnson; Yan Li; Edward L Avol; Jie Gong; Stephanie J London
Journal:  Ann Epidemiol       Date:  2004-09       Impact factor: 3.797

3.  Early childhood environment related to microbial exposure and the occurrence of atopic disease at school age.

Authors:  G de Meer; N A H Janssen; B Brunekreef
Journal:  Allergy       Date:  2005-05       Impact factor: 13.146

4.  Influence of dog ownership and high endotoxin on wheezing and atopy during infancy.

Authors:  Paloma Campo; Harpinder K Kalra; Linda Levin; Tiina Reponen; Rolanda Olds; Zana L Lummus; Seung-Hyun Cho; Gurjit K Khurana Hershey; James Lockey; Manuel Villareal; Sherry Stanforth; Grace Lemasters; David I Bernstein
Journal:  J Allergy Clin Immunol       Date:  2006-09-26       Impact factor: 10.793

5.  Childhood environment and adult atopy: results from the European Community Respiratory Health Survey.

Authors:  C Svanes; D Jarvis; S Chinn; P Burney
Journal:  J Allergy Clin Immunol       Date:  1999-03       Impact factor: 10.793

6.  High-dose exposure to cat is associated with clinical tolerance--a modified Th2 immune response?

Authors:  B Hesselmar; B Aberg; B Eriksson; B Björkstén; N Aberg
Journal:  Clin Exp Allergy       Date:  2003-12       Impact factor: 5.018

7.  Pet-keeping in early childhood and airway, nose and skin symptoms later in life.

Authors:  C G Bornehag; J Sundell; L Hagerhed; S Janson
Journal:  Allergy       Date:  2003-09       Impact factor: 13.146

8.  Cohort study of sibling effect, infectious diseases, and risk of atopic dermatitis during first 18 months of life.

Authors:  Christine Stabell Benn; Mads Melbye; Jan Wohlfahrt; Bengt Björkstén; Peter Aaby
Journal:  BMJ       Date:  2004-04-30

9.  Development of atopy and wheezing symptoms in relation to heredity and early pet keeping in a Swedish birth cohort.

Authors:  Anna Sandin; Bengt Björkstén; Lennart Bråbäck
Journal:  Pediatr Allergy Immunol       Date:  2004-08       Impact factor: 6.377

10.  Direct and indirect exposure to pets - risk of sensitization and asthma at 4 years in a birth cohort.

Authors:  C Almqvist; A-C Egmar; G Hedlin; M Lundqvist; S L Nordvall; G Pershagen; M Svartengren; M van Hage-Hamsten; M Wickman
Journal:  Clin Exp Allergy       Date:  2003-09       Impact factor: 5.018

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  8 in total

1.  A Multiple Indicators Multiple Cause (MIMIC) model of respiratory health and household factors in Chinese children: the seven Northeastern cities (SNEC) study.

Authors:  Guang-Hui Dong; Zhengmin Qian; Qiang Fu; Jing Wang; Edwin Trevathan; Wenjun Ma; Miao-Miao Liu; Da Wang; Wan-Hui Ren; Kee-Hean Ong; Tekeda Freeman Ferguson; Erin Riley; Maayan Simckes
Journal:  Matern Child Health J       Date:  2014-01

2.  Effect of prenatal indoor pet exposure on the trajectory of total IgE levels in early childhood.

Authors:  Suzanne Havstad; Ganesa Wegienka; Edward M Zoratti; Susan V Lynch; Homer A Boushey; Charlotte Nicholas; Dennis R Ownby; Christine Cole Johnson
Journal:  J Allergy Clin Immunol       Date:  2011-08-05       Impact factor: 10.793

3.  Does exposure to cats and dogs decrease the risk of allergic sensitization and disease?

Authors:  Päivi M Salo; Darryl C Zeldin
Journal:  J Allergy Clin Immunol       Date:  2009-10       Impact factor: 10.793

Review 4.  Reframing racial and ethnic disparities in atopic dermatitis in Black and Latinx populations.

Authors:  Emily A Croce; Moise L Levy; Adewole S Adamson; Elizabeth C Matsui
Journal:  J Allergy Clin Immunol       Date:  2021-09-30       Impact factor: 10.793

5.  Allergic predisposition modifies the effects of pet exposure on respiratory disease in boys and girls: the seven northeast cities of China (SNECC) study.

Authors:  Guang-Hui Dong; Jing Wang; Miao-Miao Liu; Da Wang; Yungling Leo Lee; Ya-Dong Zhao
Journal:  Environ Health       Date:  2012-07-23       Impact factor: 5.984

6.  Early life environmental predictors of asthma age-of-onset.

Authors:  Olivia R Ferry; David L Duffy; Manuel A R Ferreira
Journal:  Immun Inflamm Dis       Date:  2014-07-26

Review 7.  Primary asthma prevention: is it possible?

Authors:  Allan Becker; Moira Chan-Yeung
Journal:  Curr Allergy Asthma Rep       Date:  2008-05       Impact factor: 4.919

Review 8.  Wheezing exacerbations in early childhood: evaluation, treatment, and recent advances relevant to the genesis of asthma.

Authors:  E Kathryn Miller; Pedro C Avila; Yasmin W Khan; Carolyn R Word; Barry J Pelz; Nikolaos G Papadopoulos; R Stokes Peebles; Peter W Heymann
Journal:  J Allergy Clin Immunol Pract       Date:  2014 Sep-Oct
  8 in total

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