| Literature DB >> 17696221 |
Sharon Turban1, Paul J Thuluvath, Mohamed G Atta.
Abstract
Hepatorenal syndrome (HRS) is a "functional" and reversible form of renal failure that occurs in patients with advanced chronic liver disease. The distinctive hallmark feature of HRS is the intense renal vasoconstriction caused by interactions between systemic and portal hemodynamics. This results in activation of vasoconstrictors and suppression of vasodilators in the renal circulation. Epidemiology, pathophysiology, as well as current and emerging therapies of HRS are discussed in this review.Entities:
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Year: 2007 PMID: 17696221 PMCID: PMC4205304 DOI: 10.3748/wjg.v13.i30.4046
Source DB: PubMed Journal: World J Gastroenterol ISSN: 1007-9327 Impact factor: 5.742