Literature DB >> 17696022

Survey of atypical antipsychotic prescribing by Canadian child psychiatrists and developmental pediatricians for patients aged under 18 years.

Tamison Doey1, Kenneth Handelman, Jamie A Seabrook, Margaret Steele.   

Abstract

OBJECTIVE: To describe self-reported patterns of prescribing atypical antipsychotics (ATAs) and monitoring practices of child psychiatrists and developmental pediatricians in Canada.
METHOD: We surveyed members of the Canadian Academy of Child and Adolescent Psychiatry and members of the Developmental Paediatrics Section of the Canadian Paediatric Society regarding the types and frequencies of ATAs they prescribed, the ages and diagnoses of patients for whom they prescribed these medications, and the types and frequencies of monitoring used.
RESULTS: Ninety-four percent of the child psychiatrists (95% CI, 90% to 97%) and 89% of the developmental pediatricians (95% CI, 75% to 96%) prescribed ATAs, most commonly risperidone (69%). Diagnoses included psychotic, mood, anxiety, externalizing, and pervasive developmental disorders. Prescribing for symptoms such as aggression, low frustration tolerance, and affect dysregulation was also common. Twelve percent of all prescriptions were for children under age 9 years. Most clinicians monitored patients, but there were wide variations in the type and frequency of tests performed.
CONCLUSIONS: Despite the lack of formal indications, ATAs were prescribed by this group of clinicians for many off-label indications in youth under age 18 years, including very young children. Neither evidence-based guidelines nor a consensus on monitoring exist for this age group.

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Year:  2007        PMID: 17696022     DOI: 10.1177/070674370705200605

Source DB:  PubMed          Journal:  Can J Psychiatry        ISSN: 0706-7437            Impact factor:   4.356


  17 in total

1.  First do no harm: promoting an evidence-based approach to atypical antipsychotic use in children and adolescents.

Authors:  Constadina Panagiotopoulos; Rebecca Ronsley; Dean Elbe; Jana Davidson; Derryck H Smith
Journal:  J Can Acad Child Adolesc Psychiatry       Date:  2010-05

2.  Off-licence prescribing and regulation in psychiatry: current challenges require a new model of governance.

Authors:  Philip Sugarman; Amy Mitchell; Catherine Frogley; Geoffrey L Dickens; Marco Picchioni
Journal:  Ther Adv Psychopharmacol       Date:  2013-08

3.  Bringing a research base to psychiatry.

Authors:  Miriam Shuchman; Paul C Hébert; Rajendra Kale; Barbara Sibbald; Ken Flegel; Noni MacDonald
Journal:  CMAJ       Date:  2008-05-06       Impact factor: 8.262

4.  Trends, correlates, and disease patterns of antipsychotic use among children and adolescents in Taiwan.

Authors:  Yuan-Chang Hsu; I-Chia Chien; Happy Kuy-Lok Tan; Ching-Heng Lin; Shu-Wen Cheng; Yiing-Jenq Chou; Pesus Chou
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2013-05-08       Impact factor: 4.328

5.  Evidence for clinicians: Atypical antipsychotics for disruptive behaviour disorders in children and youths.

Authors:  Iliana Ortega
Journal:  Paediatr Child Health       Date:  2018-12-09       Impact factor: 2.253

6.  Population pharmacokinetics of oral risperidone in children, adolescents and adults with psychiatric disorders.

Authors:  An Thyssen; An Vermeulen; Eliane Fuseau; Marc-Antoine Fabre; Erik Mannaert
Journal:  Clin Pharmacokinet       Date:  2010-07       Impact factor: 6.447

7.  Interprovincial Variation in Antipsychotic and Antidepressant Prescriptions Dispensed in the Canadian Pediatric Population.

Authors:  Nikita Arora; Sandra Knowles; Tara Gomes; Muhammad M Mamdani; David N Juurlink; Corine Carlisle; Mina Tadrous
Journal:  Can J Psychiatry       Date:  2016-07-10       Impact factor: 4.356

8.  Trends in psychiatric disorders prevalence and prescription patterns of children in Alberta, Canada.

Authors:  Brenda M Y Leung; Peter Kellett; Erik Youngson; Josh Hathaway; Maria Santana
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2019-05-25       Impact factor: 4.328

9.  Child and adolescent psychiatrists' reported monitoring behaviors for second-generation antipsychotics.

Authors:  Angie Mae Rodday; Susan K Parsons; Catherine Mankiw; Christoph U Correll; Adelaide S Robb; Bonnie T Zima; Tully S Saunders; Laurel K Leslie
Journal:  J Child Adolesc Psychopharmacol       Date:  2015-04-28       Impact factor: 2.576

Review 10.  [Off-label use in child and adolescent psychiatry. An ongoing ethical, medical and legal problem].

Authors:  M Kölch; M Allroggen; J M Fegert
Journal:  Nervenarzt       Date:  2009-07       Impact factor: 1.214

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