OBJECT: In this study the authors analyzed the relationship of intraventricular hemorrhage (IVH) to in-hospital complications and clinical outcome in a large population of patients with aneurysmal subarachnoid hemorrhage (SAH). METHODS: Data from 3539 patients with aneurysmal SAH were evaluated, and these data were obtained from four prospective, randomized, double-blind, placebo-controlled trials of tirilazad that had been conducted between 1991 and 1997. Clinical characteristics, in-hospital complications, and outcome at 3 months post-SAH (Glasgow Outcome Scale score) were analyzed with regard to the presence or absence of IVH. RESULTS:Patients with SAH and IVH differ in demographic and admission characteristics from those with SAH but without IVH and are more likely to suffer in-hospital complications and a worse outcome at 3 months post-SAH. CONCLUSIONS: The presence of IVH in patients with SAH has an important predictive value with regard to these aspects.
RCT Entities:
OBJECT: In this study the authors analyzed the relationship of intraventricular hemorrhage (IVH) to in-hospital complications and clinical outcome in a large population of patients with aneurysmal subarachnoid hemorrhage (SAH). METHODS: Data from 3539 patients with aneurysmalSAH were evaluated, and these data were obtained from four prospective, randomized, double-blind, placebo-controlled trials of tirilazad that had been conducted between 1991 and 1997. Clinical characteristics, in-hospital complications, and outcome at 3 months post-SAH (Glasgow Outcome Scale score) were analyzed with regard to the presence or absence of IVH. RESULTS:Patients with SAH and IVH differ in demographic and admission characteristics from those with SAH but without IVH and are more likely to suffer in-hospital complications and a worse outcome at 3 months post-SAH. CONCLUSIONS: The presence of IVH in patients with SAH has an important predictive value with regard to these aspects.
Authors: Thomas Garton; Richard F Keep; D Andrew Wilkinson; Jennifer M Strahle; Ya Hua; Hugh J L Garton; Guohua Xi Journal: Transl Stroke Res Date: 2016-06-30 Impact factor: 6.829
Authors: Julia S Bretz; Falk Von Dincklage; Johannes Woitzik; Maren K L Winkler; Sebastian Major; Jens P Dreier; Georg Bohner; Michael Scheel Journal: Clin Neuroradiol Date: 2016-04-25 Impact factor: 3.649
Authors: Chao Gao; Hanjian Du; Ya Hua; Richard F Keep; Jennifer Strahle; Guohua Xi Journal: J Cereb Blood Flow Metab Date: 2014-03-26 Impact factor: 6.200