Literature DB >> 17694729

Prior authorization of newer insomnia medications in managed care: is it cost saving?

Rajesh Balkrishnan1, Vijay N Joish, Monali J Bhosle, Rafia S Rasu, Milap C Nahata.   

Abstract

STUDY
OBJECTIVES: New pharmacotherapeutic treatment options are available to treat patients with 1 or more insomnia symptoms. However, these new pharmaceuticals are subject to a variety of managed-care tools, such as prior authorizations, that may restrict access to these medications. The objective of this study was to evaluate the economic consequences to a health plan that requires prior authorization for nonbenzodiazepine medications approved for the treatment of insomnia characterized by difficulties both falling and staying asleep.
METHODS: An economic model was constructed to determine the effects of a typical prior-authorization program across a hypothetical managed-care population. Model parameters were derived from national estimates and a literature review.
RESULTS: Economic consequences of a prior-authorization program were based on a hypothetical managed-care plan with 500,000 insured patients. An estimated acquisition cost of $300 per 100 tablets of medication requiring prior authorization, $40 to process each priorauthorization request, and prior-authorization rejection rates of 2% to 5% were considered. Using the default-model inputs of the hypothetical plan characteristics and costs, the economic model estimated a loss of $600,000 to $700,000 per year to the health plan. In a 3-way threshold sensitivity analysis when prior-authorization rejection rate was increased to 5%, the cost of each request in the prior-authorization program was decreased to $20, and the cost of a first-generation nonbenzodiazepine was decreased to a generic price (i.e. $100 per prescription), the model continued to show a net loss to managed care in each case.
CONCLUSIONS: This model showed that requiring prior authorization for newer sleep treatments might not be a cost-saving strategy for managed-care organizations.

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Year:  2007        PMID: 17694729      PMCID: PMC1978307     

Source DB:  PubMed          Journal:  J Clin Sleep Med        ISSN: 1550-9389            Impact factor:   4.062


  23 in total

1.  Medicaid prior-authorization programs and the use of cyclooxygenase-2 inhibitors.

Authors:  Michael A Fischer; Sebastian Schneeweiss; Jerry Avorn; Daniel H Solomon
Journal:  N Engl J Med       Date:  2004-11-18       Impact factor: 91.245

2.  Prevalence, burden, and treatment of insomnia in primary care.

Authors:  G E Simon; M VonKorff
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3.  The Academy of Managed Care Pharmacy's concepts in managed care pharmacy: prior authorization and the formulary exception process.

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Journal:  J Manag Care Pharm       Date:  2005-05

4.  Physician and patient factors associated with the prescribing of medications for sleep difficulties that are associated with high abuse potential or are expensive: an analysis of data from the National Ambulatory Medical Care Survey for 1996-2001.

Authors:  Rafia S Rasu; Rahul A Shenolikar; Milap C Nahata; Rajesh Balkrishnan
Journal:  Clin Ther       Date:  2005-12       Impact factor: 3.393

Review 5.  Insomnia: therapeutic approach.

Authors:  S Lippmann; I Mazour; H Shahab
Journal:  South Med J       Date:  2001-09       Impact factor: 0.954

6.  Prevalence of insomnia: a survey of the enrollees at five managed care organizations.

Authors:  H T Hatoum; C M Kania; S X Kong; J M Wong; W B Mendelson
Journal:  Am J Manag Care       Date:  1998-01       Impact factor: 2.229

Review 7.  Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data.

Authors:  G Hajak; W E Müller; H U Wittchen; D Pittrow; W Kirch
Journal:  Addiction       Date:  2003-10       Impact factor: 6.526

8.  Sleep onset insomnia, sleep maintaining insomnia and insomnia with early morning awakening--temporal stability of subtypes in a longitudinal study on general practice attenders.

Authors:  F Hohagen; C Käppler; E Schramm; D Riemann; S Weyerer; M Berger
Journal:  Sleep       Date:  1994-09       Impact factor: 5.849

Review 9.  Comparative efficacy of newer hypnotic drugs for the short-term management of insomnia: a systematic review and meta-analysis.

Authors:  Yenal Dündar; Susanna Dodd; Judith Strobl; Angela Boland; Rumona Dickson; Tom Walley
Journal:  Hum Psychopharmacol       Date:  2004-07       Impact factor: 1.672

Review 10.  Sleep maintenance insomnia: strengths and weaknesses of current pharmacologic therapies.

Authors:  Russell P Rosenberg
Journal:  Ann Clin Psychiatry       Date:  2006 Jan-Mar       Impact factor: 1.567

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  1 in total

1.  Prevalence and factors associated with off-label antidepressant prescriptions for insomnia.

Authors:  L Leanne Lai; Mooi Heong Tan; Yen Chi Lai
Journal:  Drug Healthc Patient Saf       Date:  2011-07-08
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