OBJECTIVE: The purpose of this study was to test the hypothesis that paternal race influences the risk for preterm birth. STUDY DESIGN: We conducted a population-based cohort study to examine the association of paternal race with preterm birth using the Missouri Department of Health's birth registry from 1989-1997. Birth outcomes were analyzed in 4 categories: white mother/white father, white mother/black father, black mother/white father, and black mother/ black father. RESULTS: We evaluated 527,845 birth records. The risk of preterm birth at <35 weeks of gestation increased when either parent was black (white mother/black father: adjusted odds ratio, 1.28 [95% CI, 1.13, 1.46], black mother/white father: adjusted odds ratio, 2.10 [95% CI, 1.68, 2.62], and black mother/black father: adjusted odds ratio, 2.28 [95% CI, 2.18, 2.39]) and was even higher for extreme preterm birth (<28 weeks of gestation) in pregnancies with a nonwhite parent. CONCLUSION: Paternal black race is associated with an increased risk of preterm birth in white mothers, which suggests a paternal contribution to fetal genotype that ultimately influences the risk for preterm delivery.
OBJECTIVE: The purpose of this study was to test the hypothesis that paternal race influences the risk for preterm birth. STUDY DESIGN: We conducted a population-based cohort study to examine the association of paternal race with preterm birth using the Missouri Department of Health's birth registry from 1989-1997. Birth outcomes were analyzed in 4 categories: white mother/white father, white mother/black father, black mother/white father, and black mother/ black father. RESULTS: We evaluated 527,845 birth records. The risk of preterm birth at <35 weeks of gestation increased when either parent was black (white mother/black father: adjusted odds ratio, 1.28 [95% CI, 1.13, 1.46], black mother/white father: adjusted odds ratio, 2.10 [95% CI, 1.68, 2.62], and black mother/black father: adjusted odds ratio, 2.28 [95% CI, 2.18, 2.39]) and was even higher for extreme preterm birth (<28 weeks of gestation) in pregnancies with a nonwhite parent. CONCLUSION: Paternal black race is associated with an increased risk of preterm birth in white mothers, which suggests a paternal contribution to fetal genotype that ultimately influences the risk for preterm delivery.
Authors: Roberto Romero; Digna R Velez Edwards; Juan Pedro Kusanovic; Sonia S Hassan; Shali Mazaki-Tovi; Edi Vaisbuch; Chong Jai Kim; Tinnakorn Chaiworapongsa; Brad D Pearce; Lara A Friel; Jacquelaine Bartlett; Madan Kumar Anant; Benjamin A Salisbury; Gerald F Vovis; Min Seob Lee; Ricardo Gomez; Ernesto Behnke; Enrique Oyarzun; Gerard Tromp; Scott M Williams; Ramkumar Menon Journal: Am J Obstet Gynecol Date: 2010-05 Impact factor: 8.661
Authors: Roberto Romero; Lara A Friel; Digna R Velez Edwards; Juan Pedro Kusanovic; Sonia S Hassan; Shali Mazaki-Tovi; Edi Vaisbuch; Chong Jai Kim; Offer Erez; Tinnakorn Chaiworapongsa; Brad D Pearce; Jacquelaine Bartlett; Benjamin A Salisbury; Madan Kumar Anant; Gerald F Vovis; Min Seob Lee; Ricardo Gomez; Ernesto Behnke; Enrique Oyarzun; Gerard Tromp; Scott M Williams; Ramkumar Menon Journal: Am J Obstet Gynecol Date: 2010-07-31 Impact factor: 8.661
Authors: P C Mann; M E Cooper; K K Ryckman; B Comas; J Gili; S Crumley; E N A Bream; H M Byers; T Piester; A Schaefer; P J Christine; A Lawrence; K L Schaa; K J P Kelsey; S K Berends; A M Momany; E Gadow; V Cosentino; E E Castilla; J López Camelo; C Saleme; L J Day; S K England; M L Marazita; J M Dagle; J C Murray Journal: J Perinatol Date: 2012-09-27 Impact factor: 2.521