Literature DB >> 17689237

At identical isowork rates, ageing influences cardiorespiratory adaptations in COPD out-patients.

C Fabre1, J M Grosbois, F Bart, B Borel, P Mucci.   

Abstract

PURPOSE: To determine the extent to which younger COPD patients improve their cardiorespiratory function during exercise in comparison with older COPD patients, as a result of exercise training.
METHODS: Thirty-nine COPD patients underwent an exercise program. They were divided into two groups: a younger group (57.2+/-1.0 years, n=18 patients) and an older group (68.8+/-0.6 years, n=21 patients). Forced expiratory volume in 1s was lower than 55% of the predicted value for all patients.
RESULTS: After training, VO2 symptom-limited significantly improved by 10.3% and 8.4% for the younger and older COPD patients, respectively (P<0.05). Peak power significantly improved by 25.2% and 17.8% in the younger and older groups, respectively (P<0.05) with a greater improvement for the younger group (P<0.05). At submaximal exercise, ventilation and heart rate significantly decreased after training in the younger COPD patients (P<0.05) with no significant modification in the older COPD patients.
CONCLUSIONS: The results suggest that all patients with COPD benefit from exercise rehabilitation at maximal exercise workload, however, according to their age, submaximal cardiorespiratory adaptations were greater in younger patients.

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Year:  2007        PMID: 17689237     DOI: 10.1016/j.rmed.2007.06.016

Source DB:  PubMed          Journal:  Respir Med        ISSN: 0954-6111            Impact factor:   3.415


  1 in total

1.  Pulmonary rehabilitation for chronic obstructive pulmonary disease: clinical, economic, and budget impact analysis.

Authors: 
Journal:  CADTH Technol Overv       Date:  2010-12-01
  1 in total

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