Literature DB >> 17689231

Antinociceptive effect of Russelia equisetiformis leave extracts: identification of its active constituents.

E O Awe1, A Adeloye, T Idowu, O A Olajide, J Makinde.   

Abstract

This study examines the antinociceptive effect of the whole plant extracts of Russelia equisetiformis. The result shows the ethylacetate fraction to be the most active, while the dichloromethane fraction exhibited least activity. The major isolated compound from the ethylacetate showed a tremendous activity on acetic acid induced writhing with less activity on tail-flick response in mice. The structures of the two compounds were assigned on the basis of spectroscopic data. Occurrence of these compounds in Russelia is reported here for the first time, and the results confirm the traditional uses of R. equisetiformis in the treatment of inflammation and pain.

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Year:  2007        PMID: 17689231     DOI: 10.1016/j.phymed.2007.03.012

Source DB:  PubMed          Journal:  Phytomedicine        ISSN: 0944-7113            Impact factor:   5.340


  8 in total

1.  Free radical scavenging: a possible mechanism of action for the anti-inflammatory activity of Russelia equisetiformis (Schlect & Chan) (Scrophulariacae).

Authors:  Emmanuel Olorunju Awe; Olatunbosun S Banjoko; Modupe J Makinde
Journal:  Inflammopharmacology       Date:  2010-02-02       Impact factor: 4.473

2.  A new iridoid glycoside and NO production inhibitory activity of compounds isolated from Russelia equisetiformis.

Authors:  Madoka Ochi; Katsuyoshi Matsunami; Hideaki Otsuka; Yoshio Takeda
Journal:  J Nat Med       Date:  2011-08-06       Impact factor: 2.343

3.  Analgesic and Antiallodynic Effects of 4-Fluoro-N-(4-Sulfamoylbenzyl) Benzene Sulfonamide in a Murine Model of Pain.

Authors:  Naeem Ur Rehman; Mariya Al-Rashida; Ahmed Tokhi; Zainab Ahmed; Fazal Subhan; Muzaffar Abbas; Muhammad Awais Arshid; Khalid Rauf
Journal:  Drug Des Devel Ther       Date:  2020-10-27       Impact factor: 4.162

Review 4.  Anti-inflammatory iridoids of botanical origin.

Authors:  A Viljoen; N Mncwangi; I Vermaak
Journal:  Curr Med Chem       Date:  2012       Impact factor: 4.530

5.  Ethanol Extract of Blighia sapida Stem Bark Show Remarkable Prophylactic Activity in Experimental Plasmodium berghei-Infected Mice.

Authors:  Olayinka O Otegbade; Johnson A Ojo; Dolapo I Adefokun; Oyindamola O Abiodun; Bolaji N Thomas; Olusola Ojurongbe
Journal:  Drug Target Insights       Date:  2017-08-28

6.  Anti-inflammatory, antioxidant and antinociceptive activities of Russelia coccinea (L.) Wettst.

Authors:  María C Columba-Palomares; Rosa Mariana Montiel-Ruiz; Lucia Corona Sánchez; Daniel Palafox-Gante; Verónica Rodríguez-López
Journal:  Avicenna J Phytomed       Date:  2021 Mar-Apr

7.  In vivo Antimalarial Activities of Russelia Equisetiformis in Plasmodium Berghei Infected Mice.

Authors:  O Ojurongbe; J A Ojo; D I Adefokun; O O Abiodun; G Odewale; E O Awe
Journal:  Indian J Pharm Sci       Date:  2015 Jul-Aug       Impact factor: 0.975

8.  A Polyphenols-Rich Extract from Moricandia sinaica Boiss. Exhibits Analgesic, Anti-Inflammatory and Antipyretic Activities In Vivo.

Authors:  Sahar El-Mekkawy; Abdelaaty A Shahat; Ali S Alqahtani; Mansour S Alsaid; Mohamed A O Abdelfattah; Riaz Ullah; Mahmoud Emam; Abdelaziz Yasri; Mansour Sobeh
Journal:  Molecules       Date:  2020-10-30       Impact factor: 4.411

  8 in total

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