| Literature DB >> 17689230 |
B-S Park1, D-J Son, Y-H Park, T W Kim, S-E Lee.
Abstract
The inhibitory effects of four acidamides, piperine, pipernonaline, piperoctadecalidine, and piperlongumine, isolated from the fruits of Piper longum L. on washed rabbit platelet aggregation were examined. All of the four tested acidamides showed dose-dependent inhibitory activities on washed rabbit platelet aggregation induced by collagen, arachidonic acid (AA), and platelet-activating factor (PAF), except for that induced by thrombin. Piperlongumine, in particular, showed stronger inhibitory effects than other acidamides to rabbit platelet aggregation induced by collagen, AA and PAF.Entities:
Mesh：
Substances：
Year: 2007 PMID： 17689230 DOI： 10.1016/j.phymed.2007.06.011
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340