Literature DB >> 17687893

Impurity profile of amino acids?

Susanne Kopec1, Ulrike Holzgrabe.   

Abstract

Amino acids are produced by various manufacturing processes, i.e. chemical and enzymatic synthesis, extraction from protein hydrolysates, and fermentation. Each process produces a different impurity profile. Since the European Pharmacopoeia wants to replace the non-selective and non-sensitive "ninhydrin-positive substance" TLC test with chromatographic or electrophoretic methods limiting the impurities to 0.1 per cent, the information about the production processes and the related impurity profile is urgently needed from the manufacturers.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 17687893

Source DB:  PubMed          Journal:  Pharmeur Sci Notes        ISSN: 1814-2435


  1 in total

Review 1.  Analytical Chemistry of Impurities in Amino Acids Used as Nutrients: Recommendations for Regulatory Risk Management.

Authors:  Sachise Karakawa; Miro Smriga; Naoko Arashida; Akira Nakayama; Hiroshi Miyano
Journal:  Nutrients       Date:  2022-07-11       Impact factor: 6.706

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.