Literature DB >> 1768670

Tranexamic acid-associated ligneous conjunctivitis with gingival and peritoneal lesions.

J P Diamond1, A Chandna, C Williams, D L Easty, C Scully, J Eveson, A Richards.   

Abstract

A considerable number of agents have been proposed as causing ligneous conjunctivitis. We report the first case to arise as a side effect of tranexamic acid (Cyclokapron), an anti-fibrinolytic drug used in the treatment of menorrhagia. In addition to the typical conjunctival changes our patient had lesions affecting the gingiva and the peritoneum the last causing considerable protein loss into the peritoneal cavity.

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Year:  1991        PMID: 1768670      PMCID: PMC1042561          DOI: 10.1136/bjo.75.12.753

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  8 in total

1.  Ligneous conjunctivitis involving the cervix. Case report.

Authors:  A Rubin; D Buck; M R MacDonald
Journal:  Br J Obstet Gynaecol       Date:  1989-10

2.  Retinal artery occlusion associated with tranexamic acid therapy.

Authors:  M R Parsons; D R Merritt; R C Ramsay
Journal:  Am J Ophthalmol       Date:  1988-06-15       Impact factor: 5.258

3.  Conjunctivitis ligneosa combined with a dental affection. Report of a case.

Authors:  J Frimodt-Moller
Journal:  Acta Ophthalmol (Copenh)       Date:  1973

4.  Hereditary macrothrombocytopathia, nephritis and deafness.

Authors:  C J Epstein; M A Sahud; C F Piel; J R Goodman; M R Bernfield; J H Kushner; A R Ablin
Journal:  Am J Med       Date:  1972-03       Impact factor: 4.965

5.  Letter: Tranexamic acid and intracranial thrombosis.

Authors:  E Rydin; P O Lundberg
Journal:  Lancet       Date:  1976-07-03       Impact factor: 79.321

6.  Ligneous conjunctivitis with ear involvement.

Authors:  D M Marcus; D Walton; P Donshik; L Choo; R A Newman; D M Albert
Journal:  Arch Ophthalmol       Date:  1990-04

7.  Ophthalmological examination of patients in long-term treatment with tranexamic acid.

Authors:  P L Theil
Journal:  Acta Ophthalmol (Copenh)       Date:  1981-04

8.  Ligneous conjunctivitis. A clinicopathologic study of 17 cases.

Authors:  A A Hidayat; P J Riddle
Journal:  Ophthalmology       Date:  1987-08       Impact factor: 12.079

  8 in total
  5 in total

1.  Ligneous conjunctivitis: biochemical evidence for hypofibrinolysis.

Authors:  M L Ramsby; P C Donshik; G S Makowski
Journal:  Inflammation       Date:  2000-02       Impact factor: 4.092

2.  Ligneous conjunctivitis: a clinicopathological, immunohistochemical, and genetic study including the treatment of two sisters with multiorgan involvement.

Authors:  M Teresa Rodríguez-Ares; Ihab Abdulkader; Ana Blanco; Rosario Touriño-Peralba; Clara Ruiz-Ponte; Ana Vega; José Cameselle-Teijeiro
Journal:  Virchows Arch       Date:  2007-08-15       Impact factor: 4.064

3.  Tranexamic acid-induced ligneous conjunctivitis with renal failure showed reversible hypoplasminogenaemia.

Authors:  Youngseok Song; Naohiro Izumi; Luke Benjamin Potts; Akitoshi Yoshida
Journal:  BMJ Case Rep       Date:  2014-05-19

Review 4.  Plasminogen deficiency.

Authors:  Tiraje Celkan
Journal:  J Thromb Thrombolysis       Date:  2017-01       Impact factor: 2.300

5.  A critical role for plasminogen in inflammation.

Authors:  Sarah K Baker; Sidney Strickland
Journal:  J Exp Med       Date:  2020-04-06       Impact factor: 14.307

  5 in total

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