| Literature DB >> 17685534 |
Jae-Eun Joo1, Kee-Young Lee, Van-Thoai Pham, Yong-Shou Tian, Won-Hun Ham.
Abstract
The enantioselective total synthesis of (-)-anisomycin, a potent antibiotic agent, has been achieved. The key steps are a Pd(0)-catalyzed stereoselective intramolecular oxazine formation from d-tyrosine and pyrrolidine formation by catalytic hydrogenation of the oxazine.Entities:
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Year: 2007 PMID： 17685534 DOI： 10.1021/ol701519b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005