Literature DB >> 17685148

A pattern matching approach for the estimation of alignment between any two given DNA sequences.

K Basu1, N Sriraam, R J A Richard.   

Abstract

For a given DNA sequence, it is well known that pair wise alignment schemes are used to determine the similarity with the DNA sequences available in the databanks. The efficiency of the alignment decides the type of amino acids and its corresponding proteins. In order to evaluate the given DNA sequence for its proteomic identity, a pattern matching approach is proposed in this paper. A block based semi-global alignment scheme is introduced to determine the similarity between the DNA sequences (known and given). The two DNA sequences are divided into blocks of equal length and alignment is performed which minimizes the computational complexity. The efficiency of the alignment scheme is evaluated using the parameter, percentage of similarity (POS). Four essential DNA version of the amino acids that emphasize the importance of proteomic functionalities are chosen as patterns and matching is performed with the known and given DNA sequences to determine the similarity between them. The ratio of amino acid counts between the two sequences is estimated and the results are compared with that of the POS value. It is found from the experimental results that higher the POS value and the pattern matching higher are the similarity between the two DNA sequences. The optimal block is also identified based on the POS value and amino acids count.

Mesh:

Year:  2007        PMID: 17685148     DOI: 10.1007/s10916-007-9062-3

Source DB:  PubMed          Journal:  J Med Syst        ISSN: 0148-5598            Impact factor:   4.460


  5 in total

1.  A new approach to sequence comparison: normalized sequence alignment.

Authors:  A N Arslan; O Eğecioğlu ; P A Pevzner
Journal:  Bioinformatics       Date:  2001-04       Impact factor: 6.937

2.  [Getting the appropriate set of sequences for your research: how to use sequence retrieval system on DNA Data Bank of Japan (DDBJ)].

Authors:  M Satoru
Journal:  Tanpakushitsu Kakusan Koso       Date:  2001-05

3.  A generalized global alignment algorithm.

Authors:  Xiaoqiu Huang; Kun-Mao Chao
Journal:  Bioinformatics       Date:  2003-01-22       Impact factor: 6.937

4.  Basic local alignment search tool.

Authors:  S F Altschul; W Gish; W Miller; E W Myers; D J Lipman
Journal:  J Mol Biol       Date:  1990-10-05       Impact factor: 5.469

5.  Improved tools for biological sequence comparison.

Authors:  W R Pearson; D J Lipman
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

  5 in total
  1 in total

1.  Non-coding RNA annotation of the genome of Trichoplax adhaerens.

Authors:  Jana Hertel; Danielle de Jong; Manja Marz; Dominic Rose; Hakim Tafer; Andrea Tanzer; Bernd Schierwater; Peter F Stadler
Journal:  Nucleic Acids Res       Date:  2009-01-16       Impact factor: 16.971

  1 in total

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