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Literature DB >> 17684463

The pathophysiology of cardiovascular disease in diabetes mellitus and the future of therapy.

Joseph Emmanuel Thomas¹, JoAnne Micale Foody.

Abstract

Diabetes mellitus is a complex disease with several metabolic abnormalities leading to varied, interconnected endothelial and vascular dysfunction and resulting in accelerated atherosclerosis. Cardiovascular disease is the main cause of mortality in patients with diabetes. Apart from traditional therapy for control of hyperglycemia and other associated comorbidities, various newer therapies are being investigated to fight atherosclerosis at a molecular level. In this review, the authors briefly describe the pathophysiology of cardiovascular disease in patients with diabetes mellitus and the future of therapy.

Entities: Disease Species

Mesh：

Year: 2007 PMID： 17684463 DOI： 10.1111/j.1559-4564.2007.06046.x

Source DB: PubMed Journal: J Cardiometab Syndr ISSN： 1559-4564

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Cited

11 in total

1. Orientin inhibits high glucose-induced vascular inflammation in vitro and in vivo.

Authors: Sae-Kwang Ku; Soyoung Kwak; Jong-Sup Bae
Journal: Inflammation Date: 2014-12 Impact factor: 4.092

2. Hyperoside inhibits high-glucose-induced vascular inflammation in vitro and in vivo.

Authors: Sae-Kwang Ku; Soyoung Kwak; O-Jun Kwon; Jong-Sup Bae
Journal: Inflammation Date: 2014-10 Impact factor: 4.092

3. Fisetin inhibits high-glucose-induced vascular inflammation in vitro and in vivo.

Authors: Soyoung Kwak; Sae-Kwang Ku; Jong-Sup Bae
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4. Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) inhibits high glucose-induced inflammation in vitro and in vivo.

Authors: Sae-Kwang Ku; Soyoung Kwak; Yaesol Kim; Jong-Sup Bae
Journal: Inflammation Date: 2015-02 Impact factor: 4.092

5. High normal fasting glucose level in obese youth: a marker for insulin resistance and beta cell dysregulation.

Authors: G O'Malley; N Santoro; V Northrup; E D'Adamo; M Shaw; S Eldrich; S Caprio
Journal: Diabetologia Date: 2010-03-05 Impact factor: 10.122

6. Molecular mechanisms of hyperglycemia and cardiovascular-related events in critically ill patients: rationale for the clinical benefits of insulin therapy.

Authors: Samer Ellahham
Journal: Clin Epidemiol Date: 2010-12-12 Impact factor: 4.790

The pathophysiology of cardiovascular disease in diabetes mellitus and the future of therapy.

1. Orientin inhibits high glucose-induced vascular inflammation in vitro and in vivo.

2. Hyperoside inhibits high-glucose-induced vascular inflammation in vitro and in vivo.

3. Fisetin inhibits high-glucose-induced vascular inflammation in vitro and in vivo.

4. Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) inhibits high glucose-induced inflammation in vitro and in vivo.

5. High normal fasting glucose level in obese youth: a marker for insulin resistance and beta cell dysregulation.

6. Molecular mechanisms of hyperglycemia and cardiovascular-related events in critically ill patients: rationale for the clinical benefits of insulin therapy.

Review 7. Serum vitamin E level and gestational diabetes mellitus: a systematic review and meta-analysis.

8. Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo.

9. Percentile curves for cardiometabolic disease markers in Canadian children and youth: a cross-sectional study.

10. Dietary polyphenols as potential nutraceuticals in management of diabetes: a review.