OBJECTIVE: To study the performance of a new method designed to measure discrepancy between real prescriptions and evidence-based reference treatments. METHODS: Two different indices (additive and multiplicative) are proposed to summarize deviation between prescription and reference. Deviations thought to be observed in a population of prescribers are simulated in diverse hypothetical situations in the presence or absence of evidence-based references. The performances of both indices are compared and their sensitivities to change are explored. RESULTS: Both indices are sensitive to variation in prescriber behaviour. The additive index allows a more accurate analysis of deviation while the multiplicative index is simpler to implement and interpret but more sensitive to change. CONCLUSION: The two deviation indices may be used as new tools in surveys or trials dealing with prescribing practices.
OBJECTIVE: To study the performance of a new method designed to measure discrepancy between real prescriptions and evidence-based reference treatments. METHODS: Two different indices (additive and multiplicative) are proposed to summarize deviation between prescription and reference. Deviations thought to be observed in a population of prescribers are simulated in diverse hypothetical situations in the presence or absence of evidence-based references. The performances of both indices are compared and their sensitivities to change are explored. RESULTS: Both indices are sensitive to variation in prescriber behaviour. The additive index allows a more accurate analysis of deviation while the multiplicative index is simpler to implement and interpret but more sensitive to change. CONCLUSION: The two deviation indices may be used as new tools in surveys or trials dealing with prescribing practices.
Authors: Perry Fine; Keela Herr; Marita Titler; Sara Sanders; Joe Cavanaugh; John Swegle; Chris Forcucci; Xiongwen Tang; Kari Lane; Jimmy Reyes Journal: J Pain Symptom Manage Date: 2010-05 Impact factor: 3.612