Literature DB >> 17681762

A detailed examination of cytokine abnormalities in Major Depressive Disorder.

N M Simon1, K McNamara, C W Chow, R S Maser, G I Papakostas, M H Pollack, A A Nierenberg, M Fava, K K Wong.   

Abstract

Recent technological advances offer an opportunity to further elucidate the complex cytokine network in Major Depressive Disorder (MDD). Twenty cytokines were simultaneously assessed in 49 individuals with MDD and 49 age and gender matched controls. Multiple pro-inflammatory and two anti-inflammatory cytokines were significantly elevated in the MDD sample, including an antidepressant naïve subset. These data support a generalized chronic inflammatory state in MDD, and implicate additional cytokines and chemokines previously linked to cardiovascular disease.

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Year:  2007        PMID： 17681762      PMCID： PMC2267745          DOI： 10.1016/j.euroneuro.2007.06.004

Source DB:  PubMed          Journal:  Eur Neuropsychopharmacol        ISSN： 0924-977X            Impact factor:   4.600


  28 in total

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2.  Predictors of relapse in a prospective study of fluoxetine treatment of major depression.

Authors:  Patrick J McGrath; Jonathan W Stewart; Frederic M Quitkin; Ying Chen; Jonathan E Alpert; Andrew A Nierenberg; Maurizio Fava; Jianfeng Cheng; Eva Petkova
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3.  Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress.

Authors:  Thaddeus W W Pace; Tanja C Mletzko; Oyetunde Alagbe; Dominique L Musselman; Charles B Nemeroff; Andrew H Miller; Christine M Heim
Journal:  Am J Psychiatry       Date:  2006-09       Impact factor: 18.112

Review 4.  The many roles of chemokines and chemokine receptors in inflammation.

Authors:  Israel F Charo; Richard M Ransohoff
Journal:  N Engl J Med       Date:  2006-02-09       Impact factor: 91.245

5.  Elevated monocyte chemoattractant protein-1 serum levels in patients at risk for coronary artery disease.

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6.  Different activation patterns of proinflammatory cytokines in melancholic and non-melancholic major depression are associated with HPA axis activity.

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Journal:  J Affect Disord       Date:  2005-08       Impact factor: 4.839

7.  Inflammatory markers and the risk of coronary heart disease in men and women.

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Journal:  N Engl J Med       Date:  2004-12-16       Impact factor: 91.245

8.  Depressive symptoms and mortality in men: results from the Multiple Risk Factor Intervention Trial.

Authors:  Brooks B Gump; Karen A Matthews; Lynn E Eberly; Yue-fang Chang
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Review 9.  Cytokines sing the blues: inflammation and the pathogenesis of depression.

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Journal:  Trends Immunol       Date:  2005-11-28       Impact factor: 16.687

10.  Cytokines and serotonin transporter in patients with major depression.

Authors:  Chiung-Wen Tsao; Yee-Shin Lin; Chwen-Cheng Chen; Chyi-Huey Bai; Shin-Rung Wu
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  97 in total

Review 1.  Adolescent-Onset Depression: Are Obesity and Inflammation Developmental Mechanisms or Outcomes?

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2.  Parallel Effects of Methamphetamine on Anxiety and CCL3 in Humans and a Genetic Mouse Model of High Methamphetamine Intake.

Authors:  Marilyn Huckans; Clare J Wilhelm; Tamara J Phillips; Elaine T Huang; Rebekah Hudson; Jennifer M Loftis
Journal:  Neuropsychobiology       Date:  2018-01-18       Impact factor: 2.328

3.  Immune system dysregulation in adolescent major depressive disorder.

Authors:  Vilma Gabbay; Rachel G Klein; Carmen M Alonso; James S Babb; Melissa Nishawala; Georgette De Jesus; Glenn S Hirsch; Pauline M Z Hottinger-Blanc; Charles J Gonzalez
Journal:  J Affect Disord       Date:  2008-09-13       Impact factor: 4.839

4.  A meta-analysis of chemokines in major depression.

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Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2016-02-20       Impact factor: 5.067

5.  Corticotropin releasing factor-1 receptor antagonism alters the biochemical, but not behavioral effects of repeated interleukin-1β administration.

Authors:  Clare J Wilhelm; Aaron Murphy-Crews; Daniel J Menasco; Marilyn S Huckans; Jennifer M Loftis
Journal:  Neuropharmacology       Date:  2011-08-04       Impact factor: 5.250

6.  Anhedonia as a clinical correlate of inflammation in adolescents across psychiatric conditions.

Authors:  Rachel D Freed; Lushna M Mehra; Daniel Laor; Manishkumar Patel; Carmen M Alonso; Seunghee Kim-Schulze; Vilma Gabbay
Journal:  World J Biol Psychiatry       Date:  2018-08-16       Impact factor: 4.132

7.  The diagnosis of depression: current and emerging methods.

Authors:  Katie M Smith; Perry F Renshaw; John Bilello
Journal:  Compr Psychiatry       Date:  2012-08-15       Impact factor: 3.735

8.  Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections.

Authors:  Enrico Domenici; David R Willé; Federica Tozzi; Inga Prokopenko; Sam Miller; Astrid McKeown; Claire Brittain; Dan Rujescu; Ina Giegling; Christoph W Turck; Florian Holsboer; Edward T Bullmore; Lefkos Middleton; Emilio Merlo-Pich; Robert C Alexander; Pierandrea Muglia
Journal:  PLoS One       Date:  2010-02-11       Impact factor: 3.240

Review 9.  Blood-based biomarkers predicting response to antidepressants.

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Journal:  J Neural Transm (Vienna)       Date:  2018-01-27       Impact factor: 3.575

10.  Polymorphisms in the interleukin-10 gene cluster are possibly involved in the increased risk for major depressive disorder.

Authors:  Tanel Traks; Kati Koido; Triin Eller; Eduard Maron; Külli Kingo; Veiko Vasar; Eero Vasar; Sulev Kõks
Journal:  BMC Med Genet       Date:  2008-12-16       Impact factor: 2.103
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