| Literature DB >> 17681467 |
Daniele Andreotti1, Ilaria Bientinesi, Stefano Biondi, Daniele Donati, Isabelle Erbetti, Sergio Lociuro, Carla Marchioro, Alfonso Pozzan, Emiliangelo Ratti, Silvia Terreni.
Abstract
Synthesis and antibacterial activity of a new class of ketolide antibiotics, exemplified by the prototype GW680788X (1), are described. The structure of (1) has been elucidated by spectroscopic analysis. The good antibacterial activity shown by (1) in comparison with clarithromycin prompted us to consider this compound as a lead molecule for further exploration.Entities:
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Year: 2007 PMID： 17681467 DOI： 10.1016/j.bmcl.2007.02.019
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823