Literature DB >> 17680289

Clinical and multifocal-electroretinographic findings of congenital tilted disc syndrome associated with choroidal neovascularization: a case report.

Marilita M Moschos1, Ioannis Margetis, Spyridon Papadimitriou, Zoi Tzeni, Mihail Moschos.   

Abstract

PURPOSE: To report a case of a tilted disc syndrome associated with choroidal neovascularization.
METHODS: A 55-year-old male patient presented with blurred vision and metamorphopsia of the left eye. He underwent complete ophthalmologic examination, fluorescein angiography, optical coherence tomography (OCT) and multifocal-electroretinogram (mf-ERG).
RESULTS: All features are consistent with a tilted disc syndrome complicated with a small neovascular membrane. OCT confirmed the presence of a serous retinal detachment. Mf-ERG confirmed a decrease of electrical activity of the photoreceptors in area 1 (fovea). The patient refused to be treated.
CONCLUSION: Macular serous retinal detachment due to subretinal leakage is a rare complication of tilted disc syndrome. To the author's knowledge, this is the first time a tilted disc syndrome with choroidal neovascularization is documented by means of OCT and mf-ERG. These are the only objective tools in order to assess objectively the anatomical and functional damage accordingly.

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Year:  2007        PMID: 17680289     DOI: 10.1007/s10633-007-9067-8

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN: 0012-4486            Impact factor:   2.379


  9 in total

1.  Serous macular detachment and tilted disc syndrome.

Authors:  G Tosti
Journal:  Ophthalmology       Date:  1999-08       Impact factor: 12.079

Review 2.  Choroidal neovascularization.

Authors:  W R Green; D J Wilson
Journal:  Ophthalmology       Date:  1986-09       Impact factor: 12.079

3.  The tilted disk syndrome.

Authors:  S E Young; F B Walsh; D L Knox
Journal:  Am J Ophthalmol       Date:  1976-07       Impact factor: 5.258

4.  Retinal pigment epithelial cells release inhibitors of neovascularization.

Authors:  B M Glaser; P A Campochiaro; J L Davis; J A Jerdan
Journal:  Ophthalmology       Date:  1987-07       Impact factor: 12.079

5.  Congenital tilted disk syndrome associated with parafoveal subretinal neovascularization.

Authors:  M Stur
Journal:  Am J Ophthalmol       Date:  1988-01-15       Impact factor: 5.258

6.  Choroidal neovascularization in tilted disc syndrome.

Authors:  M Prost; J J De Laey
Journal:  Int Ophthalmol       Date:  1988       Impact factor: 2.031

7.  Chorioretinal degenerative changes in the tilted disc syndrome.

Authors:  G Giuffrè
Journal:  Int Ophthalmol       Date:  1991-01       Impact factor: 2.031

8.  Macular serous retinal detachment caused by subretinal leakage in tilted disc syndrome.

Authors:  S Y Cohen; G Quentel; B Guiberteau; C Delahaye-Mazza; A Gaudric
Journal:  Ophthalmology       Date:  1998-10       Impact factor: 12.079

Review 9.  Congenital anomalies of the optic disc.

Authors:  D J Apple; M F Rabb; P M Walsh
Journal:  Surv Ophthalmol       Date:  1982 Jul-Aug       Impact factor: 6.048

  9 in total
  3 in total

1.  Analyses of shape of eyes and structure of optic nerves in eyes with tilted disc syndrome by swept-source optical coherence tomography and three-dimensional magnetic resonance imaging.

Authors:  K Shinohara; M Moriyama; N Shimada; N Nagaoka; T Ishibashi; T Tokoro; K Ohno-Matsui
Journal:  Eye (Lond)       Date:  2013-10-11       Impact factor: 3.775

2.  Macular function in tilted disc syndrome.

Authors:  Beatrix Feigl; Andrew J Zele
Journal:  Doc Ophthalmol       Date:  2010-04       Impact factor: 2.379

3.  Tilted disc syndrome: an OCT and mfERG study.

Authors:  Marilita M Moschos; Aristides Triglianos; Tryfon Rotsos; Spyridon Papadimitriou; Ioannis Margetis; Polychronis Minogiannis; Michael Moschos
Journal:  Doc Ophthalmol       Date:  2009-01-23       Impact factor: 2.379

  3 in total

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