Literature DB >> 17680287

Functional study in NSE-Hu-Bcl-2 transgenic mice: a model for retinal diseases starting in Müller cells.

Cécile Péant1, André Dosso, Lorenza Eder-Colli, Florence Chiodini.   

Abstract

In NSE-Hu-Bcl-2 transgenic mice, line 71, retina undergoes early postnatal degeneration linked to the prior death of Müller cells. The purpose of this study was to complete the characterization of this retinal dysfunction by using electroretinographic (ERG) recordings in both scotopic and photopic conditions. Here, we showed that both rod and cone systems were profoundly affected in NSE-Hu-Bcl-2 transgenic mice as soon as 15 postnatal days in accordance with histological study performed previously.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17680287     DOI： 10.1007/s10633-007-9077-6

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN： 0012-4486            Impact factor:   2.379


  26 in total

1.  Mutation of the gene encoding cellular retinaldehyde-binding protein in autosomal recessive retinitis pigmentosa.

Authors:  M A Maw; B Kennedy; A Knight; R Bridges; K E Roth; E J Mani; J K Mukkadan; D Nancarrow; J W Crabb; M J Denton
Journal:  Nat Genet       Date:  1997-10       Impact factor: 38.330

2.  Evaluation of the rhodopsin knockout mouse as a model of pure cone function.

Authors:  G B Jaissle; C A May; J Reinhard; K Kohler; S Fauser; E Lütjen-Drecoll; E Zrenner; M W Seeliger
Journal:  Invest Ophthalmol Vis Sci       Date:  2001-02       Impact factor: 4.799

3.  Long-term survival of retinal ganglion cells following optic nerve section in adult bcl-2 transgenic mice.

Authors:  M C Cenni; L Bonfanti; J C Martinou; G M Ratto; E Strettoi; L Maffei
Journal:  Eur J Neurosci       Date:  1996-08       Impact factor: 3.386

4.  Early postnatal Müller cell death leads to retinal but not optic nerve degeneration in NSE-Hu-Bcl-2 transgenic mice.

Authors:  M Dubois-Dauphin; C Poitry-Yamate; F de Bilbao; A K Julliard; F Jourdan; G Donati
Journal:  Neuroscience       Date:  2000       Impact factor: 3.590

5.  The development of the rod photoresponse from dark-adapted rats.

Authors:  A B Fulton; R M Hansen; O Findl
Journal:  Invest Ophthalmol Vis Sci       Date:  1995-05       Impact factor: 4.799

Review 6.  Role of Muller cells in retinal degenerations.

Authors:  A Bringmann; A Reichenbach
Journal:  Front Biosci       Date:  2001-10-01

7.  Recessive mutations in the RLBP1 gene encoding cellular retinaldehyde-binding protein in a form of retinitis punctata albescens.

Authors:  H Morimura; E L Berson; T P Dryja
Journal:  Invest Ophthalmol Vis Sci       Date:  1999-04       Impact factor: 4.799

8.  Diabetes-induced dysfunction of the glutamate transporter in retinal Müller cells.

Authors:  Qing Li; Donald G Puro
Journal:  Invest Ophthalmol Vis Sci       Date:  2002-09       Impact factor: 4.799

9.  Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia.

Authors:  J C Martinou; M Dubois-Dauphin; J K Staple; I Rodriguez; H Frankowski; M Missotten; P Albertini; D Talabot; S Catsicas; C Pietra
Journal:  Neuron       Date:  1994-10       Impact factor: 17.173

10.  Behavioural visual acuity of wild type and bcl2 transgenic mouse.

Authors:  L Gianfranceschi; A Fiorentini; L Maffei
Journal:  Vision Res       Date:  1999-02       Impact factor: 1.886
View more
  1 in total

Review 1.  Relevance of Peptide Homeostasis in Metabolic Retinal Degenerative Disorders: Curative Potential in Genetically Modified Mice.

Authors:  Etelka Pöstyéni; Alma Ganczer; Andrea Kovács-Valasek; Robert Gabriel
Journal:  Front Pharmacol       Date:  2022-01-13       Impact factor: 5.810
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.