Literature DB >> 17680261

Usefulness of CT scans in malignant external otitis: effective tool for the diagnosis, but of limited value in predicting outcome.

Holger Sudhoff1, Sandeep Rajagopal, Navin Mani, Ioannis Moumoulidis, Patrick R Axon, David Moffat.   

Abstract

Computerized tomography (CT) scanning is a well recognised tool for the diagnosis of malignant external otitis. To investigate the degree of correlation between CT findings scan and the patients clinical status focusing on a subgroup of patients with cranial nerve palsies. Diagnosis of malignant external otitis was confirmed in 23 patients (average age 71 years, age range 39-87) based on criteria of severe pain, otitis externa refractory to conventional treatments and possibly diabetes mellitus and pseudomonas detection. CT was performed on 23 of these patients. Results from these scans were analysed and correlated with patient clinical status. Retrospective analysis of CT images and medical notes were used for data analysis.The CT scans of all 23 patients showed evidence of involvement of disease outside the external auditory canal, confirming the diagnosis. Sixteen out of 23 patients (70%) demonstrated evidence of bone erosion. Four of the 16 showed involvement of the petrous apex. From our subset of ten patients with cranial nerve involvement, eight demonstrated evidence of bone erosion and two showed mastoid and middle ear involvement without bone erosion. All four patients with petrous apical involvement presented with cranial nerve palsies (two lower cranial nerve palsies, one seventh nerve palsy and one combined lower and seventh nerve palsy). CT scanning was found to be a fast and economical tool in the initial assessment of patients with malignant external otitis. Petrous apex involvement was constantly associated with cranial nerve palsies, usually the lower cranial nerves. CT findings of temporal bone in itself however, were not closely correlated to the clinical outcome of the patients.

Entities:  

Mesh:

Year:  2007        PMID: 17680261     DOI: 10.1007/s00405-007-0416-8

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  15 in total

1.  Malignant external otitis: temporal bone histopathology case of the month.

Authors:  Holger Sudhoff; Fred H Linthicum
Journal:  Otol Neurotol       Date:  2003-03       Impact factor: 2.311

Review 2.  Skull base osteomyelitis. Malignant external otitis.

Authors:  W H Slattery; D E Brackmann
Journal:  Otolaryngol Clin North Am       Date:  1996-10       Impact factor: 3.346

3.  Malignant external otitis: review and personal experience.

Authors:  L Amorosa; G C Modugno; A Pirodda
Journal:  Acta Otolaryngol Suppl       Date:  1996

4.  Malignant external otitis.

Authors:  J R Chandler
Journal:  Laryngoscope       Date:  1968-08       Impact factor: 3.325

5.  Facial nerve grading system.

Authors:  J W House; D E Brackmann
Journal:  Otolaryngol Head Neck Surg       Date:  1985-04       Impact factor: 3.497

Review 6.  Malignant external otitis: insights into pathogenesis, clinical manifestations, diagnosis, and therapy.

Authors:  J Rubin; V L Yu
Journal:  Am J Med       Date:  1988-09       Impact factor: 4.965

7.  Masked pseudomonal skull base osteomyelitis presenting with a bilateral Xth cranial nerve palsy.

Authors:  R G Rowlands; G K Lekakis; A E Hinton
Journal:  J Laryngol Otol       Date:  2002-07       Impact factor: 1.469

Review 8.  The changing face of malignant (necrotising) external otitis: clinical, radiological, and anatomic correlations.

Authors:  Jennifer Rubin Grandis; Barton F Branstetter; Victor L Yu
Journal:  Lancet Infect Dis       Date:  2004-01       Impact factor: 25.071

9.  Necrotizing (malignant) external otitis.

Authors:  Ophir Handzel; Doron Halperin
Journal:  Am Fam Physician       Date:  2003-07-15       Impact factor: 3.292

10.  Evolving resistant pseudomonas to ciprofloxacin in malignant otitis externa.

Authors:  Leonard Berenholz; Udi Katzenell; Moshe Harell
Journal:  Laryngoscope       Date:  2002-09       Impact factor: 3.325

View more
  8 in total

Review 1.  Antibiotic therapy in necrotising external otitis: case series of 32 patients and review of the literature.

Authors:  C Pulcini; P Mahdyoun; E Cua; I Gahide; L Castillo; N Guevara
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2012-07-19       Impact factor: 3.267

2.  A diagnostic dilemma of central skull base osteomyelitis mimicking neoplasia in a diabetic patient.

Authors:  Aparna Dasunmalee Ganhewa; Jafri Kuthubutheen
Journal:  BMJ Case Rep       Date:  2013-01-25

3.  Technetium-99m (⁹⁹mTc)-labelled sulesomab in the management of malignant external otitis: is there any role?

Authors:  Francesco Galletti; Giovanni Cammaroto; Bruno Galletti; Natale Quartuccio; Francesca Di Mauro; Sergio Baldari
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-02-18       Impact factor: 2.503

4.  A 10-year review of malignant otitis externa: a new insight.

Authors:  Tengku Mohamed Izam Tengku Kamalden; Khairunnisak Misron
Journal:  Eur Arch Otorhinolaryngol       Date:  2021-07-05       Impact factor: 2.503

5.  Clinical Challenges in the Diagnosis and Treatment of Temporal Bone Osteomyelitis.

Authors:  Liubov Kornilenko; Saulius Rocka; Svajunas Balseris; Irina Arechvo
Journal:  Case Rep Otolaryngol       Date:  2017-04-09

6.  Skull base osteomyelitis secondary to Scedosporium apiospermum infection.

Authors:  Martin Doss; David Doss
Journal:  Radiol Case Rep       Date:  2018-06-06

Review 7.  Necrotising Otitis Externa: A Review of Imaging Modalities.

Authors:  Hammaad A Khan
Journal:  Cureus       Date:  2021-12-25

8.  Analysis of Prognostic Factors in Malignant External Otitis.

Authors:  Sang Kuk Lee; Se A Lee; Sang Woo Seon; Jae Hyun Jung; Jong Dae Lee; Jae Young Choi; Bo Gyung Kim
Journal:  Clin Exp Otorhinolaryngol       Date:  2016-09-27       Impact factor: 3.372

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.