Literature DB >> 17676748

Synthesis of the C1-C12 fragment of the tedanolides. Aldol-non-aldol aldol approach.

Michael E Jung1, Dongwon Yoo.   

Abstract

The combination of highly stereoselective non-aldol aldol and aldol processes allows the preparation of the completely protected C1-C12 fragment 2 of the novel macrocyclic cytotoxic agent tedanolide 1.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17676748     DOI： 10.1021/ol0714038

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Computational elucidation of the origins of reactivity and selectivity in non-aldol aldol rearrangements of cyclic epoxides.

Authors:  Hao Wang; K N Houk; Damian A Allen; Michael E Jung
Journal:  Org Lett       Date:  2011-05-13       Impact factor: 6.005

2.  Total syntheses of (+)-tedanolide and (+)-13-deoxytedanolide.

Authors:  Joshua R Dunetz; Lisa D Julian; Jason S Newcom; William R Roush
Journal:  J Am Chem Soc       Date:  2008-12-03       Impact factor: 15.419

3.  Asymmetric synthesis of anti-aldol segments via a nonaldol route: synthetic applications to statines and (-)-tetrahydrolipstatin.

Authors:  Arun K Ghosh; Khriesto Shurrush; Sarang Kulkarni
Journal:  J Org Chem       Date:  2009-06-19       Impact factor: 4.354
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.