Literature DB >> 1767654

Gentamicin-collagen sponge for local applications. 10 cases of chronic osteomyelitis followed for 1 year.

T Ipsen1, P S Jørgensen, V Damholt, C Tørholm.   

Abstract

A bovine collagen sponge containing gentamicin was applied locally in 10 patients with chronic osteomyelitis who were then followed for 1 year postoperatively. No adverse effects or recurrence of infections was observed. The release of gentamicin from the sponge was more complete and rapid than has been reported with polymethyl methacrylate (PMMA) beads. Compared with previous reports on PMMA beads, a much higher gentamicin concentration in the wound exudate can be expected after implantation of the collagen sponge, which is easy to apply and does not require a second operation for removal.

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Year:  1991        PMID： 1767654     DOI： 10.3109/17453679108994503

Source DB:  PubMed          Journal:  Acta Orthop Scand        ISSN： 0001-6470


  10 in total

Review 1.  Nanostructured platforms for the sustained and local delivery of antibiotics in the treatment of osteomyelitis.

Authors:  Vuk Uskokovic
Journal:  Crit Rev Ther Drug Carrier Syst       Date:  2015       Impact factor: 4.889

2.  Rare presentation of Brodie's abscess in the acromion process and the value of the penumbra sign.

Authors:  Jelle Gorter; Kyrill Rykov; Pieter Ott; Jos J A M van Raay
Journal:  BMJ Case Rep       Date:  2017-01-30

Review 3.  Infection and tissue engineering in segmental bone defects--a mini review.

Authors:  Manitha B Nair; James D Kretlow; Antonios G Mikos; F Kurtis Kasper
Journal:  Curr Opin Biotechnol       Date:  2011-02-25       Impact factor: 9.740

Review 4.  Implantable antimicrobial biomaterials for local drug delivery in bone infection models.

Authors:  Jeremy D Caplin; Andrés J García
Journal:  Acta Biomater       Date:  2019-01-14       Impact factor: 8.947

Review 5.  Therapeutics and delivery vehicles for local treatment of osteomyelitis.

Authors:  Leah H Cobb; Emily M McCabe; Lauren B Priddy
Journal:  J Orthop Res       Date:  2020-04-21       Impact factor: 3.494

6.  In vitro gentamicin release from commercially available calcium-phosphate bone substitutes influence of carrier type on duration of the release profile.

Authors:  Hein P Stallmann; Chris Faber; Antonius L J J Bronckers; Arie V Nieuw Amerongen; Paul I J M Wuisman
Journal:  BMC Musculoskelet Disord       Date:  2006-02-26       Impact factor: 2.362

7.  Comparison of Bone Preserving and Radical Surgical Treatment in 32 Cases of Calcaneal Osteomyelitis.

Authors:  Ireneusz Babiak; Piotr Pędzisz; Mateusz Kulig; Jakub Janowicz; Paweł Małdyk
Journal:  J Bone Jt Infect       Date:  2016-03-05

8.  Intra-articular implantation of collagen scaffold carriers is safe in both native and arthrofibrotic rabbit knee joints.

Authors:  J A Walker; T J Ewald; E Lewallen; A Van Wijnen; A D Hanssen; B F Morrey; M E Morrey; M P Abdel; J Sanchez-Sotelo
Journal:  Bone Joint Res       Date:  2017-03       Impact factor: 5.853

Review 9.  Recent advances in the local antibiotics delivery systems for management of osteomyelitis.

Authors:  Reem Khaled Wassif; Maha Elkayal; Rehab Nabil Shamma; Seham A Elkheshen
Journal:  Drug Deliv       Date:  2021-12       Impact factor: 6.819

10.  Clinical Efficacy of the Antibiotic-Loaded Collagen Sponge During Arthroscopic Treatment of Acute Septic Arthritis of the Native Knee.

Authors:  Kook-Jong Kim; Ho-Seung Jeong; Byung-Hyun Ahn; Dong-Min Chung
Journal:  Orthop J Sports Med       Date:  2022-04-04
  10 in total

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