Literature DB >> 17676454

The role of intrathecal baclofen in the management of primary and secondary dystonia in children.

K Woon1, M Tsegaye, M H Vloeberghs.   

Abstract

Intrathecal baclofen (ITB) is a well-established method of treating spasticity in children with cerebral palsy. In our series, eight children with primary or dystonia secondary to cerebral palsy have benefited from ITB. The observations in this paper are subjective and based on the carer's impressions, but have confirmed the role of ITB in dystonia. Children with dystonia secondary to cerebral palsy benefited most and ITB can be used in these as a single treatment modality. The approach is different in dystonia secondary to cerebral palsy, where ITB can be used to palliate the spastic component, but other methods are necessary to treat the primary disease. We currently have three children in our series, where ITB in conjunction with deep brain stimulation (DBS) was used with satisfactory results.

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Year:  2007        PMID: 17676454     DOI: 10.1080/02688690701392899

Source DB:  PubMed          Journal:  Br J Neurosurg        ISSN: 0268-8697            Impact factor:   1.596


  11 in total

1.  Intrathecal baclofen therapy for spasticity of cerebral origin--does the position of the intrathecal catheter matter?

Authors:  Gnanamurthy Sivakumar; Yoong Yap; Mekidm Tsegaye; Michael Vloeberghs
Journal:  Childs Nerv Syst       Date:  2010-03-20       Impact factor: 1.475

2.  Clinical course of patients with pantothenate kinase-associated neurodegeneration (PKAN) before and after DBS surgery.

Authors:  Marina Svetel; Aleksandra Tomić; Nataša Dragašević; Igor Petrović; Nikola Kresojević; Robert Jech; Dušan Urgošik; Isidora Banjac; Jelena Vitković; Ivana Novaković; Vladimir S Kostić
Journal:  J Neurol       Date:  2019-08-29       Impact factor: 4.849

3.  Intrathecal baclofen therapy after liver transplant in a patient with Crigler-Najjar syndrome.

Authors:  Napala R Pratini; Jacob A Neufeld
Journal:  PM R       Date:  2013-12-21       Impact factor: 2.298

4.  Treatment of classic pantothenate kinase-associated neurodegeneration with deferiprone and intrathecal baclofen.

Authors:  Napala R Pratini; Nancy Sweeters; Elliott Vichinsky; Jacob A Neufeld
Journal:  Am J Phys Med Rehabil       Date:  2013-08       Impact factor: 2.159

Review 5.  Clinical Management of Dystonia in Childhood.

Authors:  Quyen N Luc; Jyes Querubin
Journal:  Paediatr Drugs       Date:  2017-10       Impact factor: 3.930

6.  Fractional anisotropy in children with dystonia or spasticity correlates with the selection for DBS or ITB movement disorder surgery.

Authors:  Daniel E Lumsden; Jonathan Ashmore; Gareth Ball; Geoffrey Charles-Edwards; Richard Selway; Keyoumars Ashkan; Jean-Pierre Lin
Journal:  Neuroradiology       Date:  2016-01-12       Impact factor: 2.804

7.  Identification of complications in paediatric cerebral palsy treated with intrathecal baclofen pump: a descriptive analysis of 15 years at one institution.

Authors:  A Imerci; K J Rogers; C Pargas; J P Sees; F Miller
Journal:  J Child Orthop       Date:  2019-10-01       Impact factor: 1.548

Review 8.  Treating complex movement disorders in children with cerebral palsy.

Authors:  Claire Lundy; Daniel Lumsden; Charlie Fairhurst
Journal:  Ulster Med J       Date:  2009-09

Review 9.  Intrathecal baclofen for treating spasticity in children with cerebral palsy.

Authors:  Monika J Hasnat; James E Rice
Journal:  Cochrane Database Syst Rev       Date:  2015-11-13

10.  Neural stem cell transplantation for the treatment of primary torsion dystonia: A case report.

Authors:  Wen-Qing Ren; Feng Yin; Jian-Ning Zhang; Wang-Sheng Lu; Ying-Kui Liang; Josefin Adlerberth; Zeng-Min Tian
Journal:  Exp Ther Med       Date:  2016-05-25       Impact factor: 2.447

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