Literature DB >> 17676399

Vascular dynamics of a shape memory polymer foam aneurysm treatment technique.

Jason Ortega1, Duncan Maitland, Tom Wilson, William Tsai, Omer Savaş, David Saloner.   

Abstract

The vascular dynamics of a shape memory polymer foam aneurysm treatment technique are assessed through the simulated treatment of a generic basilar aneurysm using coupled fluid dynamics and heat transfer calculations. The shape memory polymer foam, which expands to fill the aneurysm when heated, is modeled at three discrete stages of the treatment procedure. To estimate an upper bound for the maximum amount of thermal damage due to foam heating, a steady velocity is specified through the basilar artery, corresponding to a minimum physiological flow velocity over a cardiac cycle. During expansion, the foam alters the flow patterns within the aneurysm by shielding the aneurysm dome from a confined jet that issues from the basilar artery. The time scales for thermal damage to the artery walls and surrounding blood flow are computed from the temperature field. The flow through the post-treatment bifurcation is comprised of two counter-rotating vortex tubes that are located beneath the aneurysm neck and extend downstream into the outlet arteries. Beneath the aneurysm neck, a marked increase in the wall shear stress is observed due to the close proximity of the counter-rotating vortex tubes to the artery wall.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17676399     DOI: 10.1007/s10439-007-9358-y

Source DB:  PubMed          Journal:  Ann Biomed Eng        ISSN: 0090-6964            Impact factor:   3.934


  13 in total

1.  Silicone Membranes to Inhibit Water Uptake into Thermoset Polyurethane Shape-Memory Polymer Conductive Composites.

Authors:  Ya-Jen Yu; Stephen Infanger; Melissa A Grunlan; Duncan J Maitland
Journal:  J Appl Polym Sci       Date:  2015-01-05       Impact factor: 3.125

2.  In vivo response to an implanted shape memory polyurethane foam in a porcine aneurysm model.

Authors:  Jennifer N Rodriguez; Fred J Clubb; Thomas S Wilson; Matthew W Miller; Theresa W Fossum; Jonathan Hartman; Egemen Tuzun; Pooja Singhal; Duncan J Maitland
Journal:  J Biomed Mater Res A       Date:  2013-05-23       Impact factor: 4.396

3.  Opacification of shape memory polymer foam designed for treatment of intracranial aneurysms.

Authors:  Jennifer N Rodriguez; Ya-Jen Yu; Matthew W Miller; Thomas S Wilson; Jonathan Hartman; Fred J Clubb; Brandon Gentry; Duncan J Maitland
Journal:  Ann Biomed Eng       Date:  2011-11-19       Impact factor: 3.934

4.  Polymeric endoaortic paving: Mechanical, thermoforming, and degradation properties of polycaprolactone/polyurethane blends for cardiovascular applications.

Authors:  J H Ashton; J A M Mertz; J L Harper; M J Slepian; J L Mills; D V McGrath; J P Vande Geest
Journal:  Acta Biomater       Date:  2010-09-09       Impact factor: 8.947

5.  Biomedical applications of thermally activated shape memory polymers.

Authors:  Ward Small; Pooja Singhal; Thomas S Wilson; Duncan J Maitland
Journal:  J Mater Chem       Date:  2010-05-14

6.  Estimation of aneurysm wall stresses created by treatment with a shape memory polymer foam device.

Authors:  Wonjun Hwang; Brent L Volk; Farida Akberali; Pooja Singhal; John C Criscione; Duncan J Maitland
Journal:  Biomech Model Mechanobiol       Date:  2011-09-08

7.  Thermomechanical properties, collapse pressure, and expansion of shape memory polymer neurovascular stent prototypes.

Authors:  Géraldine M Baer; Thomas S Wilson; Ward Small; Jonathan Hartman; William J Benett; Dennis L Matthews; Duncan J Maitland
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2009-07       Impact factor: 3.368

8.  Porous Shape Memory Polymers.

Authors:  Keith Hearon; Pooja Singhal; John Horn; Ward Small; Cory Olsovsky; Kristen C Maitland; Thomas S Wilson; Duncan J Maitland
Journal:  Polym Rev (Phila Pa)       Date:  2013-02-04

9.  Porous inorganic-organic shape memory polymers.

Authors:  Dawei Zhang; William L Burkes; Cody A Schoener; Melissa A Grunlan
Journal:  Polymer (Guildf)       Date:  2012-06-21       Impact factor: 4.430

10.  Magnetic resonance flow velocity and temperature mapping of a shape memory polymer foam device.

Authors:  Ward Small; Erica Gjersing; Julie L Herberg; Thomas S Wilson; Duncan J Maitland
Journal:  Biomed Eng Online       Date:  2009-12-31       Impact factor: 2.819

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.