Literature DB >> 17676274

Chemoenzymatic synthesis of feruloyl D-arabinose as a potential anti-mycobacterial agent.

Christina Vafiadi1, Evangelos Topakas, Luke J Alderwick, Gurdyal S Besra, Paul Christakopoulos.   

Abstract

The feruloyl esterase (StFaeC) produced by Sporotrichum thermophile transfered the feruloyl group to D: -arabinose using a mixture of n-hexane, t-butanol and water. About 45% conversion of D: -arabinose to the feruloylated derivative was achieved. The compound had an MIC value against Mycobacterium bovis BCG of 25 microg/ml.

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Year:  2007        PMID： 17676274     DOI： 10.1007/s10529-007-9440-4

Source DB:  PubMed          Journal:  Biotechnol Lett        ISSN： 0141-5492            Impact factor:   2.461


  4 in total

1.  Combining substrate specificity analysis with support vector classifiers reveals feruloyl esterase as a phylogenetically informative protein group.

Authors:  Roberto Olivares-Hernández; Hampus Sunner; Jens C Frisvad; Lisbeth Olsson; Jens Nielsen; Gianni Panagiotou
Journal:  PLoS One       Date:  2010-09-22       Impact factor: 3.240

Review 2.  Enzymatic synthesis of bioactive compounds with high potential for cosmeceutical application.

Authors:  Io Antonopoulou; Simona Varriale; Evangelos Topakas; Ulrika Rova; Paul Christakopoulos; Vincenza Faraco
Journal:  Appl Microbiol Biotechnol       Date:  2016-06-08       Impact factor: 4.813

3.  Insights into substrate binding of ferulic acid esterases by arabinose and methyl hydroxycinnamate esters and molecular docking.

Authors:  Cameron J Hunt; Io Antonopoulou; Akshat Tanksale; Ulrika Rova; Paul Christakopoulos; Victoria S Haritos
Journal:  Sci Rep       Date:  2017-12-11       Impact factor: 4.379

4.  The Inhibitory Potential of Ferulic Acid Derivatives against the SARS-CoV-2 Main Protease: Molecular Docking, Molecular Dynamics, and ADMET Evaluation.

Authors:  Io Antonopoulou; Eleftheria Sapountzaki; Ulrika Rova; Paul Christakopoulos
Journal:  Biomedicines       Date:  2022-07-25
  4 in total

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