| Literature DB >> 17673165 |
Benjamin E Brooks1, Susan K Buchanan.
Abstract
A variety of mechanisms are used to signal extracytoplasmic conditions to the cytoplasm. These mechanisms activate extracytoplasmic function (ECF) sigma factors which recruit RNA-polymerase to specific genes in order to express appropriate proteins in response to the changing environment. The two best understood ECF signaling pathways regulate sigma(E)-mediated expression of periplasmic stress response genes in Escherichia coli and FecI-mediated expression of iron-citrate transport genes in E. coli. Homologues from other Gram-negative bacteria suggest that these two signaling mechanisms and variations on these mechanisms may be the general schemes by which ECF sigma factors are regulated in Gram-negative bacteria.Entities:
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Year: 2007 PMID： 17673165 PMCID： PMC2562455 DOI： 10.1016/j.bbamem.2007.06.005
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002