Literature DB >> 17670194

Heparin induced thrombocytopenia type II complicating coronary artery bypass surgery: a tale of caution.

Uday Dandekar1, Jonathan Young, Maninder Kalkat, Christopher M R Satur.   

Abstract

OBJECTIVE: To highlight an uncommon problem of heparin induced thrombocytopenia after coronary artery bypass operation.
METHODS: We report the case of a 59-year-old man who suffered severe type II heparin induced thrombocytopenia (HIT) after coronary artery bypass operation. He experienced extensive skin necrosis at sites of saphenous vein harvesting, which progressed to cause soft tissue necrosis of both feet. He also exhibited secondary clinical features arising from pulmonary, hepatic and renal dysfunction suggestive of extensive venous thrombosis. Primary treatment of the haematological disorder was achieved by discontinuation of all forms of heparin and the administration of a heparinoid intravenously. Secondary treatment included forefoot amputations and skin grafting.
RESULTS: Though the patient suffered a protracted period of recovery he was discharged home well.
CONCLUSION: We have reported this complex case in order to familiarise cardiothoracic surgeons with the extreme characteristics of type II HIT and to emphasise that early diagnosis and treatment will facilitate a successful outcome.

Entities:  

Year:  2004        PMID: 17670194     DOI: 10.1016/S1569-9293(03)00231-7

Source DB:  PubMed          Journal:  Interact Cardiovasc Thorac Surg        ISSN: 1569-9285


  1 in total

1.  Heparin induced thrombocytopenia-type 2.

Authors:  Tanveer A Majeed
Journal:  Asian J Transfus Sci       Date:  2010-07
  1 in total

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