Literature DB >> 17669563

Recombinant capripoxviruses expressing proteins of bluetongue virus: evaluation of immune responses and protection in small ruminants.

Aurélie Perrin1, Emmanuel Albina, Emmanuel Bréard, Corinne Sailleau, Sylvie Promé, Colette Grillet, Olivier Kwiatek, Pierre Russo, Richard Thiéry, Stephan Zientara, Catherine Cêtre-Sossah.   

Abstract

The development of recombinant capripoxviruses for protective immunization of ruminants against bluetongue virus (BTV) infection is described. Sheep (n=11) and goats (n=4) were immunized with BTV recombinant capripoxviruses (BTV-Cpox) individually expressing four different genes encoding two capsid proteins (VP2 and VP7) and two non-structural proteins (NS1, NS3) of BTV serotype 2 (BTV-2). Seroconversion was observed against NS3, VP7 and VP2 in both species and a lymphoproliferation specific to BTV antigens was also demonstrated in goats. Finally, partial protection of sheep challenged 3 weeks after BTV-Cpox administration with a virulent strain of BTV-2, was observed.

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Year:  2007        PMID： 17669563     DOI： 10.1016/j.vaccine.2007.06.052

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  25 in total

1.  Infection of nonhost species dendritic cells in vitro with an attenuated myxoma virus induces gene expression that predicts its efficacy as a vaccine vector.

Authors:  S Top; E Foulon; B Pignolet; M Deplanche; C Caubet; C Tasca; S Bertagnoli; G Meyer; G Foucras
Journal:  J Virol       Date:  2011-08-10       Impact factor: 5.103

2.  Protection of sheep against Rift Valley fever virus and sheep poxvirus with a recombinant capripoxvirus vaccine.

Authors:  Reuben K Soi; Fred R Rurangirwa; Travis C McGuire; Paul M Rwambo; James C DeMartini; Timothy B Crawford
Journal:  Clin Vaccine Immunol       Date:  2010-09-28

Review 3.  Prospects for improved bluetongue vaccines.

Authors:  Polly Roy; Mark Boyce; Robert Noad
Journal:  Nat Rev Microbiol       Date:  2009-02       Impact factor: 60.633

4.  Purification, stability, and immunogenicity analyses of five bluetongue virus proteins for use in development of a subunit vaccine that allows differentiation of infected from vaccinated animals.

Authors:  Jenna Anderson; Emmanuel Bréard; Karin Lövgren Bengtsson; Kjell-Olov Grönvik; Stéphan Zientara; Jean-Francois Valarcher; Sara Hägglund
Journal:  Clin Vaccine Immunol       Date:  2014-01-22

5.  A protective bivalent vaccine against Rift Valley fever and bluetongue.

Authors:  Eva Calvo-Pinilla; Alejandro Marín-López; Sandra Moreno; Gema Lorenzo; Sergio Utrilla-Trigo; Luis Jiménez-Cabello; Julio Benavides; Aitor Nogales; Rafael Blasco; Alejandro Brun; Javier Ortego
Journal:  NPJ Vaccines       Date:  2020-07-30       Impact factor: 7.344

6.  Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep.

Authors:  Cristina C P Celma; Mark Boyce; Piet A van Rijn; Michael Eschbaumer; Kerstin Wernike; Bernd Hoffmann; Martin Beer; Andy Haegeman; Kris De Clercq; Polly Roy
Journal:  J Virol       Date:  2013-07-03       Impact factor: 5.103

7.  Evaluation of the immunogenicity of an experimental subunit vaccine that allows differentiation between infected and vaccinated animals against bluetongue virus serotype 8 in cattle.

Authors:  Jenna Anderson; Sara Hägglund; Emmanuel Bréard; Loic Comtet; Karin Lövgren Bengtsson; John Pringle; Stéphan Zientara; Jean Francois Valarcher
Journal:  Clin Vaccine Immunol       Date:  2013-05-29

8.  Dendritic cell subtypes from lymph nodes and blood show contrasted gene expression programs upon Bluetongue virus infection.

Authors:  Suzana Ruscanu; Luc Jouneau; Céline Urien; Mickael Bourge; Jérôme Lecardonnel; Marco Moroldo; Benoit Loup; Marc Dalod; Jamila Elhmouzi-Younes; Claudia Bevilacqua; Jayne Hope; Damien Vitour; Stéphan Zientara; Gilles Meyer; Isabelle Schwartz-Cornil
Journal:  J Virol       Date:  2013-06-19       Impact factor: 5.103

9.  Generation of replication-defective virus-based vaccines that confer full protection in sheep against virulent bluetongue virus challenge.

Authors:  Eiko Matsuo; Cristina C P Celma; Mark Boyce; Cyril Viarouge; Corinne Sailleau; Eric Dubois; Emmanuel Bréard; Richard Thiéry; Stéphan Zientara; Polly Roy
Journal:  J Virol       Date:  2011-07-27       Impact factor: 5.103

10.  Engineering of Recombinant Sheep Pox Viruses Expressing Foreign Antigens.

Authors:  Olga Chervyakova; Elmira Tailakova; Nurlan Kozhabergenov; Sandugash Sadikaliyeva; Kulyaisan Sultankulova; Kunsulu Zakarya; Rinat A Maksyutov; Vitaliy Strochkov; Nurlan Sandybayev
Journal:  Microorganisms       Date:  2021-05-07
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