BACKGROUND: We have studied the tracking (i.e., the correlation between subsequent measurements) of serum lipids in a cohort of 2,236 children and adolescents (ages initially 3-18 years). METHODS: Determinations of the serum variables were made 3 and 6 years apart. Six-year tracking values (Spearman's r) were 0.63, 0.66, 0.58, and 0.36 for serum total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides, respectively. Boys were found to track better than girls. Subjects who remained persistently in the highest (total cholesterol, low-density lipoprotein cholesterol, and triglycerides) or lowest (high-density lipoprotein cholesterol and high-density lipoprotein ratio) quintile tended to become obese and smoked cigarettes more frequently than the others. CONCLUSION: The tracking of high-density lipoprotein cholesterol was higher than in previous studies, but differences in methodology may account for this. We conclude that total cholesterol and low-density as well as high-density lipoprotein cholesterol measurements in childhood and adolescence are predictive of adult values.
BACKGROUND: We have studied the tracking (i.e., the correlation between subsequent measurements) of serum lipids in a cohort of 2,236 children and adolescents (ages initially 3-18 years). METHODS: Determinations of the serum variables were made 3 and 6 years apart. Six-year tracking values (Spearman's r) were 0.63, 0.66, 0.58, and 0.36 for serum total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides, respectively. Boys were found to track better than girls. Subjects who remained persistently in the highest (total cholesterol, low-density lipoprotein cholesterol, and triglycerides) or lowest (high-density lipoprotein cholesterol and high-density lipoprotein ratio) quintile tended to become obese and smoked cigarettes more frequently than the others. CONCLUSION: The tracking of high-density lipoprotein cholesterol was higher than in previous studies, but differences in methodology may account for this. We conclude that total cholesterol and low-density as well as high-density lipoprotein cholesterol measurements in childhood and adolescence are predictive of adult values.
Authors: Markus Juonala; Feitong Wu; Alan Sinaiko; Jessica G Woo; Elaine M Urbina; David Jacobs; Julia Steinberger; Ronald Prineas; Juha Koskinen; Matthew A Sabin; David P Burgner; Trudy L Burns; Lydia Bazzano; Alison Venn; Jorma S A Viikari; Nina Hutri-Kähönen; Stephen R Daniels; Terence Dwyer; Olli T Raitakari; Costan G Magnussen Journal: Pediatrics Date: 2020-03-24 Impact factor: 7.124
Authors: Costan G Magnussen; Harri Niinikoski; Markus Juonala; Mika Kivimäki; Tapani Rönnemaa; Jorma S A Viikari; Olli Simell; Olli T Raitakari Journal: Pediatr Nephrol Date: 2011-08-30 Impact factor: 3.714
Authors: Maureen Dobbins; Steven E Hanna; Donna Ciliska; Steve Manske; Roy Cameron; Shawna L Mercer; Linda O'Mara; Kara DeCorby; Paula Robeson Journal: Implement Sci Date: 2009-09-23 Impact factor: 7.327