BACKGROUND: A dentinogenic ghost cell tumor is a locally invasive neoplasm that is characterized by ameloblastoma-like islands of epithelial cells in a mature connective tissue stroma. METHODS: A 43-year-old male patient presented a well-circumscribed sessile, exophytic mass of the gingiva with a diameter of 2 cm located in the canine area of the right maxilla. The lesion was enucleated. RESULTS: The lesion showed odontogenic epithelium, ghost cells, dentinoid material, and giant cells. The final microscopic diagnosis was a dentinogenic ghost cell tumor. CONCLUSIONS: A dentinogenic ghost cell tumor is an extremely rare tumor, and only a few cases have been reported in the English literature. The peripheral, extraosseous lesion can be easily confused with other gingival lesions such as reactive or inflammatory lesions or other peripheral odontogenic tumors. The clinical appearance of all of these lesions is similar; therefore, the definitive diagnosis depends on histology, and a biopsy with a microscopic examination is mandatory.
BACKGROUND: A dentinogenic ghost cell tumor is a locally invasive neoplasm that is characterized by ameloblastoma-like islands of epithelial cells in a mature connective tissue stroma. METHODS: A 43-year-old male patient presented a well-circumscribed sessile, exophytic mass of the gingiva with a diameter of 2 cm located in the canine area of the right maxilla. The lesion was enucleated. RESULTS: The lesion showed odontogenic epithelium, ghost cells, dentinoid material, and giant cells. The final microscopic diagnosis was a dentinogenic ghost cell tumor. CONCLUSIONS: A dentinogenic ghost cell tumor is an extremely rare tumor, and only a few cases have been reported in the English literature. The peripheral, extraosseous lesion can be easily confused with other gingival lesions such as reactive or inflammatory lesions or other peripheral odontogenic tumors. The clinical appearance of all of these lesions is similar; therefore, the definitive diagnosis depends on histology, and a biopsy with a microscopic examination is mandatory.
Authors: Caio César da Silva Barros; Maurília Raquel de Souto Medeiros; Roberto Almeida de Azevedo; Márcia Cristina da Costa Miguel; Jean Nunes Dos Santos; Éricka Janine Dantas da Silveira Journal: Oral Maxillofac Surg Date: 2021-02-14
Authors: Margherita Tumedei; Eitan Mijiritsky; Carlos Fernando Mourão; Adriano Piattelli; Marco Degidi; Carlo Mangano; Giovanna Iezzi Journal: Int J Environ Res Public Health Date: 2022-06-28 Impact factor: 4.614
Authors: Annas Salleh; Zainal Z Zainuddin; Reza M M Tarmizi; Chee K Yap; Chian-Ren Jeng; Mohd Zamri-Saad Journal: Animals (Basel) Date: 2021-04-20 Impact factor: 2.752