OBJECTIVES: To review cases of ocular syphilis presenting to a tertiary uveitis clinic during a syphilis epidemic in France between January 2001 and January 2004. STUDY DESIGN: Retrospective chart and patient database review. RESULTS: Ten patients who presented with symptoms and signs of uveitis tested positive for active syphilis. Some of the patients also presented with a rash or headache. Human immunodeficiency virus (HIV) antibody testing was positive in eight of the 10 patients, with CD4 cell counts >200 cells/mm3 in seven of the patients. Ocular inflammation resolved and visual acuity improved in all patients after treatment. CONCLUSIONS: A diagnosis of ocular syphilis should be considered in any patient with visual loss associated with a rash or headache, irrespective of the patient's CD4 cell count. Ocular syphilis in HIV-positive patients should be treated as neurosyphilis, whereas ocular syphilis in non-HIV patients can be treated as secondary syphilis.
OBJECTIVES: To review cases of ocular syphilis presenting to a tertiary uveitis clinic during a syphilis epidemic in France between January 2001 and January 2004. STUDY DESIGN: Retrospective chart and patient database review. RESULTS: Ten patients who presented with symptoms and signs of uveitis tested positive for active syphilis. Some of the patients also presented with a rash or headache. Human immunodeficiency virus (HIV) antibody testing was positive in eight of the 10 patients, with CD4 cell counts >200 cells/mm3 in seven of the patients. Ocular inflammation resolved and visual acuity improved in all patients after treatment. CONCLUSIONS: A diagnosis of ocular syphilis should be considered in any patient with visual loss associated with a rash or headache, irrespective of the patient's CD4 cell count. Ocular syphilis in HIV-positivepatients should be treated as neurosyphilis, whereas ocular syphilis in non-HIVpatients can be treated as secondary syphilis.
Authors: Jonathan Z Li; Joseph D Tucker; Ann-Marie Lobo; Christina M Marra; Benjamin T Davis; George N Papaliodis; Donna Felsenstein; Marlene L Durand; Sigal Yawetz; Gregory K Robbins Journal: Clin Infect Dis Date: 2010-08-15 Impact factor: 9.079
Authors: Joseph D Tucker; Jonathan Z Li; Gregory K Robbins; Benjamin T Davis; Ann-Marie Lobo; Jan Kunkel; George N Papaliodis; Marlene L Durand; Donna Felsenstein Journal: Sex Transm Infect Date: 2010-08-26 Impact factor: 3.519
Authors: Anna B Cope; Victoria L Mobley; Sara E Oliver; Mara Larson; Nicole Dzialowy; Jason Maxwell; Jessica L Rinsky; Thomas A Peterman; Aaron Fleischauer; Erika Samoff Journal: Sex Transm Dis Date: 2019-02 Impact factor: 2.830