| Literature DB >> 17666190 |
Cara L Ferreira1, Suzanne Lapi, Jennifer Steele, David E Green, Thomas J Ruth, Michael J Adam, Chris Orvig.
Abstract
Bis-ligand cobalt(II) complexes of four 3-hydroxy-4-pyridinone ligands with pendant carbohydrates were synthesized and examined for their potential as radiopharmaceuticals. Non-radioactive complexes were prepared on the macroscopic scale and characterized by elemental analysis, mass spectrometry, IR and UV/visible spectroscopy. Facile radiolabeling produced the 55Co complexes in high radiochemical yields (>95%). Identification of the radiolabeled compounds was accomplished by HPLC comparison with the corresponding non-radioactive complexes.Entities:
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Year: 2007 PMID： 17666190 DOI： 10.1016/j.apradiso.2007.06.003
Source DB: PubMed Journal: Appl Radiat Isot ISSN： 0969-8043 Impact factor: 1.513