BACKGROUND: To evaluate cervical length changes as predictors of preterm delivery. METHODS: Two hundred and fifty-seven pregnant women underwent transvaginal ultrasound examination at 16 and 24 weeks of gestation. Cervical length was measured and the difference between the 2 measurements was calculated. The sensitivity, specificity, positive predictive value and negative predictive value of cervical length and cervical length changes were calculated and these methods were compared by receiver-operating characteristic (ROC) curve analysis. RESULTS: Preterm delivery (before 37 weeks of gestation) occurred in 19 patients (7.4%). The mean cervical length was shorter in the preterm group, the area under the ROC curve for prediction of preterm delivery was 0.914, ultrasound had a sensitivity of 84.2% to predict preterm delivery with a false-positive rate of 18.5%, and the relative risk was 4.56 at the 34.3-mm cutoff value at 24 weeks of gestation. In contrast, a cervical length change on transvaginal ultrasound had a sensitivity of 73.3% to predict preterm delivery with a false-positive rate of 18.1%, and the relative risk was 4.08 at the 6.6-mm cutoff value. CONCLUSION: A single cervical length measurement obtained at 24 weeks of gestation can predict preterm delivery as accurately as cervical length change. 2007 S. Karger AG, Basel
BACKGROUND: To evaluate cervical length changes as predictors of preterm delivery. METHODS: Two hundred and fifty-seven pregnant women underwent transvaginal ultrasound examination at 16 and 24 weeks of gestation. Cervical length was measured and the difference between the 2 measurements was calculated. The sensitivity, specificity, positive predictive value and negative predictive value of cervical length and cervical length changes were calculated and these methods were compared by receiver-operating characteristic (ROC) curve analysis. RESULTS: Preterm delivery (before 37 weeks of gestation) occurred in 19 patients (7.4%). The mean cervical length was shorter in the preterm group, the area under the ROC curve for prediction of preterm delivery was 0.914, ultrasound had a sensitivity of 84.2% to predict preterm delivery with a false-positive rate of 18.5%, and the relative risk was 4.56 at the 34.3-mm cutoff value at 24 weeks of gestation. In contrast, a cervical length change on transvaginal ultrasound had a sensitivity of 73.3% to predict preterm delivery with a false-positive rate of 18.1%, and the relative risk was 4.08 at the 6.6-mm cutoff value. CONCLUSION: A single cervical length measurement obtained at 24 weeks of gestation can predict preterm delivery as accurately as cervical length change. 2007 S. Karger AG, Basel
Authors: Lindsay M Kindinger; Maria Kyrgiou; David A MacIntyre; Stefano Cacciatore; Angela Yulia; Joanna Cook; Vasso Terzidou; T G Teoh; Phillip R Bennett Journal: PLoS One Date: 2016-11-03 Impact factor: 3.240
Authors: U-B Wennerholm; L Valentin; T Wikström; P Kuusela; B Jacobsson; H Hagberg; P Lindgren; M Svensson Journal: Ultrasound Obstet Gynecol Date: 2022-06 Impact factor: 8.678