Literature DB >> 17664866

The complexity of age-related hearing impairment: contributing environmental and genetic factors.

E Van Eyken1, G Van Camp, L Van Laer.   

Abstract

Age-related hearing impairment (ARHI) is the most common sensory impairment seen in the elderly. It is a complex disorder, with both environmental as well as genetic factors contributing to the impairment. The involvement of several environmental factors has been partially elucidated. A first step towards the identification of the genetic factors has been made, which will result in the identification of susceptibility genes, and will provide possible targets for the future treatment and/or prevention of ARHI. This paper aims to give a broad overview of the scientific findings related to ARHI, focusing mainly on environmental and genetic data in humans and in animal models. In addition, methods for the identification of contributing genetic factors as well as possible future therapeutic strategies are discussed. (c) 2007 S. Karger AG, Basel.

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Mesh：

Year:  2007        PMID： 17664866     DOI： 10.1159/000106478

Source DB:  PubMed          Journal:  Audiol Neurootol        ISSN： 1420-3030            Impact factor:   1.854


  100 in total

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