| Literature DB >> 17663690 |
Mona Beaunoyer1, Jason M Vanatta, Makoto Ogihara, Debra Strichartz, Gary Dahl, William E Berquist, Ricardo O Castillo, Kenneth L Cox, Carlos O Esquivel.
Abstract
HBL and HCC are the most common hepatic malignancies in children. The role of OLT in children with HCC is still a matter of debate. The aim of this study was to review our experience of OLT for HCC. Medical records of patients (<18 yr) who underwent OLT for HCC were reviewed and compared to children who underwent OLT for HBL and for indications other than malignancy. There were 25 patients: HCC (10 cases) and HBL (15 cases). The actuarial patient survival for HCC at one and five yr was 100% and 83.3%, for the HBL group the survival was 86.7% at both one and five yr, and for indications (n=377) other than malignancy the patient survival for pediatric OLT at our center was 87.7% and 84.7% at one and five yr, respectively. The actuarial recurrence free survival at five yr was 83.3% for HCC and 66.8% for HBL. In conclusion, OLT is a good therapeutic modality for children with HCC and HBL.Entities:
Mesh：
Year: 2007 PMID： 17663690 DOI： 10.1111/j.1399-3046.2007.00751.x
Source DB: PubMed Journal: Pediatr Transplant ISSN： 1397-3142