| Literature DB >> 17663464 |
Chul Hoon Kim1, Jinu Lee, Jae-Youn Lee, Katherine W Roche.
Abstract
Metabotropic glutamate receptors (mGluRs) play important roles in neurotransmission, neuronal development, synaptic plasticity, and neurological disorders. Recent studies have revealed a sophisticated interplay between mGluRs and protein kinases: activation of mGluRs regulates the activity of a number of kinases, and direct phosphorylation of mGluRs affects receptor signaling, trafficking, and desensitization. Here we review the emerging literature on mGluR phosphorylation, signaling, and synaptic function.Entities:
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Year: 2008 PMID: 17663464 DOI: 10.1002/jnr.21437
Source DB: PubMed Journal: J Neurosci Res ISSN: 0360-4012 Impact factor: 4.164