| Literature DB >> 17661905 |
Abstract
Aging is associated clinically with increases in the frequency and severity of infectious diseases and an increased incidence of cancer, chronic inflammatory disorders and autoimmunity. These age-associated immune dysfunctions are the consequence of declines in both the generation of new naïve T and B lymphocytes and the functional competence of memory populations. These alterations collectively are termed immunosenescence.Entities:
Mesh：
Year: 2007 PMID： 17661905 DOI： 10.1111/j.1399-0039.2007.00891.x
Source DB: PubMed Journal: Tissue Antigens ISSN： 0001-2815